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The Oxford vaccine trial was discontinued due to a suspected serious adverse reaction in one of the participants.
Investigators have stopped the trial while investigating the unexplained illness of a volunteer in the UK.
“As part of the ongoing global randomized controlled trials of the Oxford coronavirus vaccine, our standard review process was activated and we voluntarily stopped vaccination to allow review of safety data by an independent committee.” said a spokesman for AstraZeneca, the drug maker that works with Oxford. University – he said.
They explained that it was a “routine action” and that it is expediting the investigation to minimize any potential impact on the trial schedule.
“We are committed to the safety of our participants and to the highest standards of conduct in our trials,” they added.
The nature of the adverse reaction and when it occurred is currently unknown.
Clinical withholdings generally mean there is a hiatus in recruiting new participants and dosing current ones.
It’s not uncommon for trials to be suspended, but scientists are under pressure to develop a vaccine to help curb the disease. pandemic.
The most serious adverse reactions that occur after vaccination are not related to the injection and are overlapping health problems, the World Health Organization (WHO) said.
When a vaccine is given to a large number of people, some people are likely to experience a medical problem at the time of vaccination, but this does not prove any cause and effect.
Still, investigators will need to investigate whether there is any link.
In July, the first results of the trial showed that the vaccine was safe and produced strong immune responses in volunteers.
No unexpected adverse reactions were recorded at that time, although more than half of the 1,000 participants reported mild or moderate side effects including fever, headaches, muscle aches, and pain at the injection site.
A scientist from the Oxford Vaccine Group works in the laboratory
Phase three trials of the Oxford vaccine had recently expanded to the US, recruiting up to 30,000 adults.
Trials were also underway in South Africa and Brazil.
Experts believe that finding a vaccine is the only way to get the world back to normal in the future, and there are currently nine candidate vaccines in larger phase three trials.
But how well a vaccine will work is not known, and America’s leading infectious disease expert Dr. Anthony Fauci recently warned that the chances of it being nearly 100% effective “are not great.”
“We still don’t know what the efficacy might be. We don’t know if it will be 50% or 60%. I would like it to be 75% or more,” he said.
