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| Venue of events: Olympic Stadium, Rome Date: Saturday October 31 Kick off: 16:45 GMT |
| Coverage: Live on BBC Radio 5 Live with live text on the BBC Sport website and app |
| Highlight: Watch it on the BBC Sport website and app after the game. |
Exeter’s winning double lock Jonny Hill will make his England debut in Saturday’s Six Nations game against Italy in Rome.
Hill starred as the Chiefs won a national and European double this month and joins Maro Itoje in the second row.
Scrum half Ben Youngs wins his 100th game, becoming the second Englishman to do so after Jason Leonard.
England could seal the Six Nations title with a victory if France v Ireland’s result goes well.
Hooker Tom Dunn and backups Ollie Lawrence and Ollie Thorley are set for their debut off the bench.
In addition to Youngs, starting hooker Jamie George reaches a milestone at the Stadio Olimpico by winning his 50th international game.
Even with a bonus point win, England wouldn’t be confirmed Six Nations champions until after France played Ireland.
England will face Italy
Furbank; Watson, Joseph, Slade, May; Farrell, Youngs; M Vunipola, George, Sinckler, Itoje, Hill, Curry, Underhill, B Vunipola.
Replacements: Dunn, Genge, Stuart, Ewels, Earl, Robson, Lawrence, Thorley.
New faces arrive as the injured list grows
The presence of four unlimited players on Matchday 23 comes as head coach Eddie Jones struggles with an ever-growing list of injured players.
Wasps scrum-half Dan Robson is set to win his third international game off the bench after Willi Heinz was ruled out on wednesday with a leg injury.
With elevated middle George Ford and center Manu Tuilagi unavailable, Captain Owen Farrell will start at 10 and will be joined by Henry Slade and Jonathan Joseph in midfield.
Northampton’s George Furbank starts at 3pm in the absence of Elliot Daly, with Exeter hooker Luke Cowan-Dickie, clubmate Jack Nowell, Joe Marler and Courtney Lawes also injured.
Wasps fly-half Jacob Umaga has been overlooked, leaving no obvious 10 on the bench, but Jones suggested earlier in the week that he had been testing Furbank at that position.
Forwards coach Matt Proudfoot said the Wasps flanker is fit Jack Willis was “ready for the rugby test” but the 23-year-old has not made the squad, with Bristol’s Ben Earl on the bench.
