UK coronavirus variant looks more deadly, study suggests, but more research is needed



The sample of infected people in the UK was found to be between 32% and 104% – hence the probable 64% – more deaths than people infected with previously circulating variants, according to a study published in the medical journal BMJ on Wednesday.
This variant was originally found to be more easily transmissible and new data support claims by UK authorities based on preliminary data, which variant could be even more fatal.

Researchers from various UK institutions analyzed data from more than 100,000 patients who tested positive for Covid-19 between October and January, and followed up until mid-February.

Researchers took a closer look at the tests by which the variables were examined compared to previous rotating variables.

This study showed that the new variant was associated with 227 deaths in a sample of 54790 patients – compared to 141 deaths in the same number of patients infected with the previous strain.

“In the community, death from COVID-19 is still a rare occurrence, but the B.1.1.7 variant carries a higher risk. Together with its ability to spread rapidly, this makes the B.1.1.7 a threat that should be taken seriously,” in the UK. Robert Chellen, lead author of the University of Exeter study, said in a news release on Wednesday.
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Dr. Amesh Adalaja, a senior scholar at the Johns Hopkins University Center for Health Protection, says more research is needed to determine exactly what happens during an infection caused by a B1.1.7 variant. , Told CNN on Wednesday. In the study, the patient’s covid-19 posed a greater risk of death associated with the variant around two weeks during the illness.

“This is a clear divorce after two weeks – so the authors think I want to understand more about what happens,” said Adalja, who was not involved in the new study.

“Could it be that they have a bacterial infection because they have been in the hospital for a long time? Are they more likely to have blood clots? What is the complication of this delay in death?” Adalaja said. “This was what I found most interesting.”

From the new study B.1.1. Increasing our understanding of the var variant is Lawrence Young, a virologist at the University of Warwick in Europe and a professor of molecular oncology at Europe, who encourages a recent increase in infections in Europe that were not involved. The new study, said in a statement distributed Wednesday by the Science Media Center.

“This study confirms previous work showing that infection with the type B1.1.7 virus is associated with an increased risk of death,” Young said in part. “The exact mechanisms responsible for the increased mortality associated with the variant are uncertain, but with high levels of virus replication as well as increased transmissibility.”

Juices Tange, an honorary associate professor and clinical virologist at the University of Leicester, said in a statement that he was “still not very confident” of the results from the study.

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The coldest winter temperatures can exacerbate underlying conditions – such as chronic heart, lung, kidney and neurological diseases – that can lead to more serious covid-19 or even death, Tang said in a distribution by the Science Media Center. Tang said in a distribution by Media Center. .

He said this change is really needed in the spring to take into account the cold weather factor, as well as other seasonal variables.

Further research is also needed to determine whether similar findings will emerge in more patients in other parts of the world.

In the United States, for example, this type is changing, and health officials warn that it could be “influential” in the country.

“In addition to being more transmissible, the type of anxiety seems to be more lethal,” the researchers wrote in their study. “We expect this to be associated with a mutation in its phenotypic properties due to multiple genetic mutations, and we see no reason why this finding would be specific to the UK.”

As variants of the B1.1..7 continue to spread in the UK, Adalja said the nation should pay close attention to the growing risk of death.

“If we take this to be true – this contagion is more lethal, in addition to being more lethal – it emphasizes the need to get vaccinated quickly in the hands of the people, because we know that our vaccines are stable and strong against this variant,” Adalaja said. . “The better we vaccinate people, the harder it will be.”

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