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The drug Molnupiravir, developed by American flu scientists, neutralized the new type of coronavirus (Covid-19) in 24 hours in animal experiments. World-renowned Turkish professor Derya Unutmaz stated that she expects the results of the drug to be apparent in a couple of months. It was said that the drug could be innovative.
According to the NTV news, Researchers from the Institute of Biomedical Sciences of Georgia State University in the USA, In the experiments of “MK-4482 / EIDD-2801”, a new antiviral drug developed against influenza, in poppies, completely neutralize the new type of coronavirus in 24 hours and reduce the risk of transmission. He found that it prevented it. The drug, also known as molnupravir, was developed by a team led by Professor Dr. Richard Plemper.
Professor Plemper said: “This is the first drug that can rapidly prevent the transmission of Covid-19 and can be taken orally. MK-4482 / EIDD-2801 can be a game changer,” he said.
THE RESULTS OF ONE TWO MONTHS ARE DETERMINED
Working as a principal investigator at the Jackson Laboratory Institute in the United States, Prof. Dr. Derya does not forget, “This drug, called Molnupiravir, used in the treatment of influenza, has been shown in animal experiments to completely destroy the coronavirus within 24 hours. Phase 2/3 human trials are currently underway and show promise. The effect will be evident in treatment with covid19 for one or two months. used expressions.
VACCINES CAN BLOCK PAPER
However, successful vaccines have been developed against the epidemic that infected more than 70 million people around the world. Pfizer / PioNTech, Moderna and the Gamelaya Institute announced that they have developed vaccines that provide 95 percent, 94 percent, and 95 percent protection, respectively.
However, the widespread use of these vaccines to create herd immunity in society is expected to last next spring in developed countries and years in poor countries.
In this process, stopping the spread of Covid-19 is vital to mitigate the devastating economic and social consequences of the pandemic. If molnupiravir achieves the result in poppies in human experiments, it could play a key role as a vaccine in the fight against the pandemic.
THE DRUG CAN STOP YOU
On the other hand, the effect of the vaccines developed on the asymptomatic spread is unknown. The reason for this is that the vaccine trials are based only on Covid-19 patients showing symptoms and the effect of the virus on the nose, which is the source of entry, is unclear.
However, since molnupiravir directly affects the respiratory tract, it has the potential to prevent it. However, Turkish scientist Uğur Şahin, founding partner of BioNTech, stated that it could take a year to determine whether the vaccine will stop asymptomatic cases.
Plember explained that because the drug can be taken orally, clinical trials can be started early to potentially achieve multiple benefits. These benefits are as follows. It will prevent people from contracting severe Covid-19 disease, the emotional and socioeconomic impact of their long-term isolation will decrease, and local epidemics will end quickly.
“We realized early on that molnupiravir has broad spectrum activity against RNA viruses that affect the respiratory tract, and oral treatment of infected animals with drugs reduces the amount of viral particles emitted and significantly reduces transmission. These characteristics made Molnupiravir a strong candidate for the pharmacological control of Covid-19 “ Plember, along with his team in the study published in Nature Microbiology, redesigned the drug against Covid-19 and tested it on a ferret to test the effect of the drug in stopping the spread of the virus.
DR. TUTKU TAŞKINOĞLU
Dr. Tutku Taşkınoğlu, a specialist in clinical microbiology, in a statement he recently made, “Human trials began in June. Studies are underway in 1,300 or 1,800 people. If the results of that study are announced, it will be ready to be launched as an effective drug against this virus. A drug with proven superiority over placebo according to the announced data “. used expressions.
PREVENTED DISEASE
Researcher Dr. Robert Cox, “The new type of coronavirus spreads quite easily among poppies, but for the most part it does not develop serious disease, which is very similar to the spread of Covid-19 in young adults.” said.
The scientists then infected the ferrets with a new type of coronavirus, and when the animals began to spread the virus through their noses, they began treatment with molnupiravir.
The other study author, Josef Wolf, “When we housed the infected together and then put the untreated animals in the same cage, none of those that were in contact with the coronavirus became ill. However, all the ferrets that received placebo became infected. If we can treat the patients with molnupiravir, their virus in the oral and nasal flora is completely We can destroy them and lose their contamination in 24 hours, thus avoiding the spread of asymptomatic patients. made the explanation.
IN THE SECOND STAGE IN HUMAN TESTING
Finally, the scientists claimed that the drug is currently in the final stage of advanced second-stage lockin trials against Covid-19 infection to verify the drug’s effectiveness in preventing transmission of the virus.
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