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The meaning of the mutation, the statement of the Minister of Health, Fahrettin Koca, was one of the topics that they focused on together. In Turkey, the coronavirus related to the seen and unseen mutations of her husband, the ministers issued a written statement through social networks. Minister Koca reported that flights from England were stopped and mutations were observed in 15 people. The mutation, which does not change the normal combination of inherited material, means that all the change in the hereditary structure is divided into three. Experts say that, unlike the antigenic structure change in the virus, it can be good.
MINISTER KOCA’S EXPLANATION OF MUTATION
The Minister of Health, Fahrettin Koca, announced that when entering the country, 15 people were detected carrying a mutation of the coronavirus originating in England.
Minister Koca said in his statement, “In investigations carried out for mutation originating in England, mutated viruses were detected in 15 people who entered the country from this country and were taken under control. Entries from England to the country were temporarily stopped.
WHAT IS MUTATION?
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According to the information contained in the COVID-19 Dictionary published by the Ministry of Health, mutation;
Permanent change in the genetic material of an organism or virus.
Many more mutations occur in RNA viruses than in DNA viruses. SARS-CoV-2 is an RNA virus.
Mutation or change are permanent changes that occur in the DNA or RNA sequence within the genome of a living being. The mutated organism is called a mutant. Due to the detrimental effects of mutations in genes, organisms have mechanisms such as DNA repair to eliminate mutations.
Infectious Disease Specialist Dr. Songül Özer answered the basic confusing questions about the mutation for readers of Hürriyet Aile.
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IS THE MOST DANGEROUS MUTATED CORONAVIRUS?
There is the possibility of mutation in all viruses, that is, “changing variants”. This probability is higher with some viruses. Mutations can occur more frequently and in less time in influenza and coronavirus. Antigenic modification should not always be considered wrong. The virus has changed its antigenic structure, it has created a new crime, now there is no need to fear that there will be more deaths or more spread. Sometimes the antigenic structure change in the virus can be in the opposite direction.
In the explanations made in line with the studies carried out, it is stated that the contamination of the newly detected virus is greater, but it is less likely to cause death or serious illness, what we call fatality among patients. In fact, this is a good situation. The more polluted, it does not mean that it is worse. We are interested in whether patients have a heavy life or whether patients cause death. It can infect many people, but they can be mild. In a sense, this is a good situation as it will increase immunity in society. When the number of patients and survivors increases, they are vaccinated naturally. They gain immunity by transmitting the disease, which is the most desired image we call active immunization.
DOES THE BODY GIVE A DIFFERENT RESPONSE TO MUTATION?
If the variant has had an antigenic structure change with a low ability to cause disease, the body will of course respond slightly to the disease. For example, we became infected with the virus in 2020, but at the end of 2020 a new antigenic virus appeared, we can contract it and reinfect it. We can get sick again. The body can react like the first. It’s about what mutation is. If the virus has become a great capacity to produce disease, of course, we will spend more when we take it. But if the ability to cause disease is reduced, we will have our second infection, or if we have it for the first time, we will have it in a milder way. It is important what type of mutation the virus has undergone, what antigenic structure has changed.
ARE VACCINES EFFECTIVE AGAINST THE MUTATED VIRUS?
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A vaccine is made with the virus crimes in question. We can produce antibodies against what we know, what we find. It is not possible for us to be vaccinated against something we do not see. Vaccine studies from the United States, England, Russia, Germany and China were the most prominent. These countries have produced vaccines against the virus that they have seen since December 2019. If we apply the vaccines that they developed to people, it will protect us against those viruses. It is not possible that the vaccines produced by the Germans and China are effective against the newly released virus, which have completed the production phase that has reached us and are in the distribution phase. Therefore, it will not protect against a new virus. The same goes for the flu. The reason we give the vaccine to humans every year is that its antigenic nature changes. The previous year’s vaccine does not protect this year. The same will probably happen with the Covid-19 vaccine.
