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Tekirdağ Namık Kemal University Hospital Chief Physician Chest Disease Specialist Assoc. Dr. Nejat Altıntaş conducted assessments on Covid-19, which mutated in England and the transmission rate increased by 70 percent. Let’s say the virus attaches itself to the body Altıntaş, “There are bumps on the virus. We call them spike proteins. When we look at the structure of the spike protein, the spike protein consists of two subparts. One part is called the S1 part and the other is the S2 part. The virus comes first. We breathe. It comes from the sick person, enters through the nose through the mouth. There are some binders in our body, the places where it sticks. These are mainly found in the lungs. In our kidneys and intestines. So the virus comes and attaches itself to these places. The place where it attaches itself is called AC2. It attaches itself to the receptors, S1. “After sticking to the back, the S1 part it follows from there. With the S2 part, the virus enters the cell and invades our cells. “
‘THE VIRUS IS INVISIBLE TO DEFENSE CELLS’
Stating that there have been three changes to the virus mutation in the UK, Assoc. Dr. Altıntaş, “Mutation means change. There has been a change in the area where the spike protein is located. The name of a mutation is the N501Y mutation. What is the N501Y mutation? The S1 protein binds much better to the receptor AC 2, the receptor that attaches to the body. It attaches itself much faster. The probability of coming to us and staying with us has increased. Apart from this, a second mutation has occurred. The second mutation is called the P681H mutation. Afterwards After the virus arrives and attaches itself, S1 and S2 must break down to get in. Proteins S1 and S2 break down. It started to enter the cell much more easily. Adhesion increased in the first mutation. In the second mutation, it entered into the cell. When it entered the cell, the defense cells tried to capture and destroy it. The virus also tried to escape from it. It developed a new mutation. SPIKE6970 DEL mutation. With this, the virus has now become invisible to our cells. ulas of defense. Our cells that will defend the virus do not see this. Therefore, its contagiousness has increased by 70 percent now. Go from person to person easier, faster. In this sense, has the virus worsened? Or if we look to see if the virulence of the virus has increased, there is no change in the lethality of the virus. Second, there are no changes in the severity of the disease. Where is the change? As we speak, it happens much faster with the mechanisms we have described. We have seen it now, especially in England, followed by the Netherlands and South Africa. Countries have closed their borders for precautionary reasons. It is important that these measures are taken on time. We act very fast. We immediately closed our borders. We will see the positive effects of this in the long term, ”he said.
Noting that measures must continue in the same way to protect against the mutated virus, Assoc. Dr. Altıntaş emphasized that the mask is important. Stating that even if the virus has changed, there are no changes in the possibility, diameter and size of the mask, Altıntaş stated that there is a decrease in the number of patients.
‘INTENSIVE CARE BEDS BEGIN TO EMPTY’
Stating that the number of patients increased from 33,000 to 19,000 in 10 days, Altıntaş said: “If this continues, our number will start to decrease a lot. Especially when we look at our own insides, we see it personally. Our university beds have started to be empty. Our intensive care beds have started to empty. We have become extremely comfortable. “
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‘THE CHINESE VACCINE IS EXTREMELY SAFE’
Assoc. Dr. Stating that the Chinese vaccine is safe in coronavirus, Nejat Altıntaş said: “The German vaccine, the vaccines produced by the Biontech company and the Pfizer or Moderna company in the US, not the virus itself, but the genetic code of the place where the virus attaches itself to our body, giving the peak protein in our body “. The Chinese vaccine is a virus that has died. They first reproduce the virus in an environment. Then they kill it in an alcohol called formaldehyde. It is then administered to the body. This vaccine is a vaccine that everyone learned with the tuberculosis vaccine in 1895 for centuries. The Sinovac company, from which we buy the vaccine, is one of the most advanced vaccine companies in the world, because it is the first company in the world to find the Hepatitis A vaccine, which we all have at the moment. The company that brought and markets the Hepatitis A vaccine that no one has ever had without question. the vaccine is extremely reliable. The mutation occurred in the spike protein. The effect of the German vaccine or Moderna’s vaccine may be reduced due to the change in structure in the peak protein. Because the region where the virus is attached began to change. That virus is different, the current virus is another. If this virus changes so quickly, it may not be effective. But if China’s vaccine is against everything from the whole virus, there may not be a decrease in its effectiveness. Of course we don’t know them. These are just our predictions, “he said.
