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According to the news on the “Clinical Trials Arena” website, studies of the candidate vaccine called “Ad5-NCov” will be carried out in Moscow in cooperation with the Russian pharmaceutical manufacturer Petrovax.
The goal is to start stage 3 trials in different countries of the world for the candidate vaccine called “Ad5-NCov”, which CanSino has developed in cooperation with the Chinese Military Medical Academy, starting in September. Studies are planned in Pakistan, Saudi Arabia, Brazil, Russia and Chile for the stage 3 trials.
Stage 1 and 2 clinical trials were conducted in China, where the safety and immunological effect of Ad5-nCOV, which aims to evoke immune responses by transferring the genetic components of Covid-19 to the body, were carried out in China. human with a harmless adenovirus that causes the common cold.
VACCINATION STUDIES IN CHINA
In China, where Covid-19 appeared, clinical trials of 8 candidate vaccines continue. 4 of these are tested in humans in the first, 4 in the second and third stages.
Public pharmaceutical companies such as CanSino, Sinopharm and Sinovac carry out vaccination studies in cooperation with institutions such as the Chinese Military Medical Academy, the Wuhan Institute of Virology and the Beijing Institute of Biological Products.
Aside from the CanSino vaccine candidate, the vaccine candidates developed by Sinopharm with the Vuhan Institute of Virology and the Beijing Institute of Biological Products and the “CoronaVac” developed by SinoVac are among the most promising studies.
CLINICAL TRIALS ARE PERFORMED IN 3 STAGES
For a vaccine to be widely used, it must be tested in humans in 3 stages.
In the first phase of clinical trials, the vaccine’s safety and possible side effects are being investigated in a small number of healthy volunteers. In the second stage, the effectiveness of the vaccine, whose reliability has been confirmed, is tested in more than 100 subjects. In the third and last stage the same process is repeated with thousands of subjects. This whole process can take months or even years.
33 VACCINE CANDIDATES IN CLINICAL TRIAL
According to data from the World Health Organization (WHO), as of August 28, 33 candidate vaccines against Covid-19 are in clinical trials and 143 candidate vaccines are in the preclinical evaluation stage.
Covid-19, which originated in China, spread to more than 200 countries and regions and became an epidemic. Although the number of cases exceeded 26 million worldwide, more than 867 thousand people died.
