Antihypertensive drugs do not appear to affect Covid-19 infection.



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Many people in Germany take antihypertensive drugs.

Many people in Germany take antihypertensive drugs.

Guido Mieth / Getty Images

  • Three studies published in the New England Journal of Medicine see no link between taking hypotensive medications and Covid infection 19.
  • Therefore, the course of the disease is not influenced by the medication. This suspicion had been raised in advance by doctors.
  • Hypertension is one of the most common chronic diseases in Germany and is generally treated with medication.

Many questions about transmission, disease course, and options for protection against the new coronavirus have yet to be definitively answered. However, scientists have now been able to solve a puzzle about the virus: antihypertensive drugs do not increase the risk of developing Covid-19.

This fear was expressed after it became clear how the virus used up its uneven surface. With the help of the structure, the virus manages to bind to receptors on cells in the throat or lungs. Then it penetrates and infects them. These are the same receptors on which the drugs that regulate blood pressure act.

Hypertension is one of the most common chronic diseases.

Then doctors suspected that the drugs could make it easier for the virus to infect cells and spread. Animal testing had suggested such an effect. Since hypertension is one of the most common chronic diseases and drug treatment is common, this hypothesis worries many people.

But now scientists are giving the clear. Three studies published in the “New England Journal of Medicine” indicate that there is no connection between the risk of infection and antihypertensive agents. Nor was fear confirmed that the drug could promote a severe course of the disease.

As the “Spiegel” reported in relation to the studies, the researchers focused on two groups of drugs: ACE inhibitors and angiotensin receptor blockers. These include the medications Valsartan, Lisinopril and Losartan, which are often prescribed in Germany.

Three different studies with the same result.

In a first study, which analyzed the health data of 8,910 Covid-19 patients from eleven countries, several factors were found to be related to the risk of death. These include advanced age (over 65 years), COPD lung disease, coronary artery disease, as well as regular smoking. However, taking antihypertensive drugs had no effect on the risk of death.

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In a second study, a US research team. USA He analyzed data from the Lombardy region in northern Italy. First, they wanted to find out if taking antihypertensive medications affects the risk of infection. They compared data from around 6,000 people infected with Covid-19 with those from just under 31,000 people who did not have the disease. A connection between an increased risk of infection and the agents could not be demonstrated. The same was true for a suspicious relationship between a severe course of the disease and taking the drug.

The third investigation was devoted to the medical records of more than 12,000 US patients. USA They had undergone the Covid 19 test. Almost half of the cases examined had received a positive result. About 1,000 of them were seriously ill. The researchers found no difference between the people taking antihypertensive drugs and other study participants.

Therefore, all three studies independently reached the same conclusion. “I am happy to be able to tell my patients that they can continue to take their hypertension medications,” says “Spiegel” Harmony Reynolds of the New York University School of Medicine. She had conducted the third study.

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