Harzt supply chain expansion: Pfizer only delivers half of expected vaccine doses – News



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  • Pfizer has cut its delivery target for the corona vaccine in half this year.
  • As a reason for the delay, the US pharmaceutical company informed the Wall Street Journal that the expansion of the supply chain was delayed.
  • Furthermore, the results of the clinical study became available later than originally thought, according to Pfizer.

According to the Wall Street Journal, Pfizer maintained its internal goal of delivering 100 million doses of vaccines by the end of this year through mid-November. More recently, however, the company only spoke of 50 million cans.

For next year, the original plan to administer more than 1 billion doses of vaccines will be maintained, the newspaper wrote.

Two doses per person are necessary

Those who get vaccinated need two doses to be protected. Pfizer developed the vaccine together with German manufacturer Biontech from Mainz.

In the newspaper report, citing a person involved in vaccine development, it was said that some components did not meet standards in initial production. The group did not initially respond to a request for more information.

The British Medicines Agency granted Pfizer and Biontech emergency approval for their corona vaccine on Wednesday. The UK is the first country to issue a certificate of authorization for the vaccine. The US Food and Drug Administration and the European Medicines Agency Ema are also reviewing these applications.

US Emergency Approval Scheduled for December

In the US, emergency approval is expected in mid-December. According to this week, the US government expects to have Pfizer’s corona vaccine available to 6.4 million people by the end of the year. Additionally, by the end of the year, 12.5 million people in the US could also receive the vaccine from the biotech company Moderna, whose approval process is also ongoing.

In addition to Biontech / Pfizer, several other pharmaceutical companies are currently working on advanced-stage corona vaccines, including Johnson & Johnson, Astrazeneca, and Sanofi-GSK. Countries like Russia, China and recently Bahrain have already launched vaccines with restrictions and are already vaccinating parts of the population.

Sources: Nature- Florian Krammer; NEW; FDAhttps://www.nature.com/articles/s41586-020-2798-3https://www.nytimes.com/interactive/2020/04/30/opinion/coronavirus-covid-vaccine.htmlhttps://de.wikipedia.org/wiki/Klinische_Studie?veaction=edit§ion=6The vaccine sprintIt usually takes a lot Years, a vaccine develop. The corona pandemic forces companies Institutes and authorities to new ways.COVID-19vaccineNormal ProcessAccelerated ProcessproductionAdmission1 2345678 910eleven121314fifteenYearsYearsWith risk in No admissionPhase III nach early Between-analysisRolling processbased on existing Processes of SARS and MERS Designdeveloping15 years or moreproductionseveral yearsClinic testsCompatibility tests (~ 20-80 people)Phase i12 yearsDesignPreclinical Experiments and Design one possible Vaccineseveral years10-18 monthsClinic testsIIIIIIdevelopingDevelopment of Production process and toxicological studies (Animal testing)2-4 yearsAdmission12 yearsLicenseby the authoritiesPhase ii2 yearsClinic testsReview concept, Determination of the dose(~ 50-200 people)Clinic testsPhase III23 yearsEffectiveness test Commercial approval of the therapy(~ 1000+ people)

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