Kidney injury observed in more than a third of hospitalized patients with COVID-19: study of EE. USA



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CHICAGO: More than a third of patients treated for COVID-19 in a large New York medical system developed acute kidney damage and nearly 15 percent required dialysis, US researchers reported Thursday (May 14).

The study was conducted by a team at Northwell Health, New York State’s largest healthcare provider.


“We found that in the first 5,449 admitted patients, 36.6 percent developed an acute kidney injury,” said study co-author Dr. Kenar Jhaveri, associate chief of nephrology at Hofstra / Northwell in Great Neck, New York, whose findings They were published in the magazine Kidney International.

Acute kidney injury occurs when the kidneys fail and become unable to filter waste.

Of those kidney failure patients, 14.3 percent required dialysis, Jhaveri said in a phone interview.

The study is the largest to date to analyze kidney injury in patients with COVID-19. Jhaveri said it may be helpful, as other hospitals are facing new waves of patients with the disease caused by the new coronavirus that has infected more than 4.3 million people and killed more than 295,000 worldwide.

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Several groups have observed higher rates of kidney failure among COVID-19 patients. Jhaveri and his colleagues set out to quantify it by reviewing the medical records of 5,449 COVID-19 patients hospitalized between March 1 and April 5.

They found that kidney failure occurred early, with 37.3 percent of patients arriving at the hospital with kidney failure, or developing the condition within the first 24 hours of admission.

In many cases, kidney failure occurred around the time that seriously ill patients had to be placed on a ventilator, Jhaveri said.

Among the more than 1,000 patients who needed to be placed on a ventilator, approximately 90 percent developed acute kidney failure. That compares with 21.7 percent of the 925 patients who developed the condition but did not need mechanical respiratory support.

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Very sick patients often develop kidney failure as their conditions become increasingly severe, Jhaveri said.

“It is not specific to COVID-19. It is more related to how sick you are,” he said.

However, knowing the proportion of patients at risk for this condition could help hospitals as they plan the equipment and staffing needed for future waves of coronavirus, he said.

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