Months after the coronavirus epidemic, researchers are still investigating the actual incident where the novel coronavirus crossover occurred from animal to human. According to a study published in Nature Microbiology, a team of scientists may have been searching for an answer to a question for months.
A group of scientists from the United States, China, and Europe compared the mutation patterns of SARS-COVID-2, the virus that causes COVID-19, compared it to other viruses, and made an evolutionary history of the related virus. The study said they discovered the lineage responsible for producing the virus that created the COVID-19 epidemic, which is present in bats, the study said.
Scientists have discovered the lineage responsible for producing the virus that caused the COVID-19 epidemic, which is present in bats, the study said.
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“Collectively, our analysis indicates that SARS-CV-2 is the main reservoir of bats. While it is possible that pangolins, or other hitherto unknown species, may act as intermediate hosts to facilitate transmission in humans, the current evidence is consistent with viruses evolving from bats, resulting in bats being cervicoviruses that can mimic both in the upper respiratory tract. Humans and pangolins, ”the study authors said in a published report.
The novel coronavirus evolved from another bat virus 40-70 years ago, the team of researchers said.
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The authors write that the SARS-COV-to lineage has not gone unnoticed in bats for decades.
In a news release to Fox News, the researchers said that the RATG-13 coronavirus-like SARS-Covey-2 found genetically (about 96%) in a sample of Rhinolofus Effinis Horseshoe Boat in China’s Yunnan Province in 2013 was genetically identical (about 96%). From.
“In collaboration with the Department of Evolutionary and Computational Virology, Chief Investigator, Philip Lemmy, we have developed the ability to estimate the time of variability after developing a history of recurrence, leading to an insight into the origins of many different viral pathogens.” Said in the publication.
The novel coronavirus shares a receptor-binding domain (RBD) related trait on its spike protein with older members of its lineage, allowing it to bind with human receptor cells, the authors said.
“Its receptor-binding purpose, important for the specificity of human ACE2 receptors, appears to be an ancestral trait shared with the BAT virus and not one recently achieved by recombination.”
“This means that other viruses capable of infecting humans are circulating in China,” explains David Robertson, co-author of the study, who is a professor of computational virology at the MRC-University of the Gersko Center for Glasgow Center. In publication.
The authors of the study said that other groups of researchers suggest that evolutionary changes in pangolins are incorrect in transmitting the novel coronavirus to humans. “The RBD sequence of SARS-Cavi-2 has so far been found in only a few pangolin viruses,” Robertson said.
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“While it is possible that pangolins acted as a central host for the delivery of SARS-Cove-2 to humans, there is no evidence to suggest that pangolin infection is a need for the bat virus to enter humans.” Report. “Instead, our research suggests that SARS-COV-2 may have developed the ability to mimic the upper respiratory tract of both humans and pangolins.”
Implementation systems for real-time monitoring of human diseases and better sampling of bats are needed to detect new infectious microorganisms and prevent future epidemics, the authors said in the publication.
“The key to successful surveillance is to know which viruses to detect and prioritize for people who can easily infect humans,” Robertson said. We should be better prepared for another SARS virus. “
