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A man and a woman were killed in the shooting, Acting Police Chief Mark Simmons said.
The 14 injured people were taken to two different hospitals, Simmons said, noting that none of the injured was at risk of death.
“This is truly a tragedy of epic proportions,” Simmons said near the crime scene.
The shooting comes at a time when the city police department was affected by the suffocation death of Daniel Prude.
A video shot in March and released by Prude’s family on September 4 shows Prude handcuffed and naked, as one officer pushes his face to the ground on the street while another officer presses one knee into his back.
The officers pushed him to the ground for about two minutes until he stopped breathing.
A week later, Prude’s life support was removed.
On Monday, Mayor Lovely Warren fired Police Chief La’Ron Singletary, claiming he initially misled her about the circumstances of Prude’s death.
