[ad_1]
The panel of international experts, experts from around the world who are part of a WHO guideline development group, does not suggest the use of the drug in hospitalized patients with covid-19, whether or not they are in serious condition, due to lack of evidence . influencing survival or need for ventilation.
Remdesivir has been identified as a potentially effective treatment for severe cases of Covid-19 and is widely used to treat hospitalized people.
The now published recommendation, according to a WHO statement, is based on a new review of the evidence, comparing the effects of various anti-covid-19 drugs, and includes data from four international trials involving more than 7,000 people. hospitalized with covid-19. .
After a comprehensive review of the evidence, the expert panel concluded that remdesivir “does not have a significant effect on mortality or other important patient outcomes, such as the need for ventilation or the rate of improvement,” the statement said.
The experts emphasized that there is no evidence that remdesivir has any benefit for patients. And they advise against its use, either because of the possibility of side effects or because of its administration (intravenous).
On October 16, the WHO released the results of a sponsored trial, according to which the drugs remdesivir and interferon were not effective in fighting COVID-19.
That same day, at a press conference, the director general of the WHO, Tedros Adhanom Ghebreyesus, said that so far the corticosteroid dexamethasone was the only therapy proven to be effective against COVID-19 in patients with serious diseases.
Tedros Adhanom Ghebreyesus said WHO officials noted that interim trials showed that remdesivir and interferon “have little or no effect in preventing death from COVID-19 or reducing hospitalization time.” And he noted that it was the largest trial ever conducted, involving 13,000 people from 500 hospitals in 30 countries.
The results of the study were questioned by US pharmacist Gilead (who developed the antiviral), who said they appeared “inconsistent”, noting that other trials validate the benefit of the antiviral.
The covid-19 pandemic caused at least 1,350,275 deaths derived from more than 56.2 million cases of infection worldwide, according to a report prepared by the French agency AFP.
In Portugal, 3,701 people died from the 243,009 confirmed cases of infection, according to the most recent bulletin from the Directorate General of Health.
