The Novavax vaccine shows an effectiveness greater than 89%



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“A NVX-CoV2373 has the potential to play an important role in solving this global public health crisis, “said Company Manager Stanley. Erck.

However, the vaccine is much less effective against the variant first identified in the Africa South, which scientists consider most contagious.

The company will immediately launch development of a new version of the vaccine targeting this variant, according to the statement.

The clinical trials, conducted in the UK, involved 15,000 people aged 18 to 84, 27% of whom were over 65.

The first interim analysis was based on 62 cases of COVID-19-19, of which 56 were observed in the placebo group, compared to six cases among those who received the vaccine NVX– CoV2373.

The company’s preliminary analysis indicates that the variant first identified in England, B.1.1.7, was detected in more than 50% of confirmed cases.

The efficacy of the vaccine by strain of coronavirus it was estimated at 95.6% compared to the original strain and 85.6% compared to the variant that appeared in the United Kingdom.

But the effectiveness appears to be much lower in a smaller study conducted in Africa From the south.

The latter involved just over 4,400 patients, of September medium janeiro, a period during which variant B.1.351 was widely spread over Africa From the south.

The overall effectiveness of the vaccine was 49.4% in these trials, but the number increased to 60% among 94% of the participants. seronegative for him HIV.

A Novavax said it began researching new vaccines against emerging variants in early janeiro and it hopes to detect ideal vaccine candidates in the coming days, before starting clinical trials in the second trimester.

Unlike the Pfizer and Moderna vaccines, which use RNA, a injection of the vaccine Novavax includes fragments of coronavirus that allow to trigger an immune response in the human body.

Preliminary Findings May Help Novavax to obtain authorization for its vaccine in Great Britain, but the US government. U.S is funding a much larger study that is still recruiting volunteers.

A pandemic from COVID-19-19 caused at least 2.1 million deaths as a result of more than 100 million cases of infection around the world, according to a report by the French agency AFP.

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