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Test
Tests – animal experiments – conducted in France and the United States pointed to promising antiviral efficacy and toxicity.
A study published this Tuesday in the journal Science reveals that a Spanish drug has shown an almost total reduction in the viral load of the new coronavirus. It is the drug plitidepsin, a drug used in tumors.
Tests – animal experiments – conducted in France and the United States pointed to promising antiviral efficacy and toxicity.
In two different animal experiments in which there was SARS-CoV-2 infection, a 99 percent reduction in viral load was achieved in lungs treated with plitidepsin. In light of this, the study authors argue that the drug plitidepsin should be tested in large clinical trials.
In the article published in Science, it is also explained that the drug works by blocking the human protein eEF1A, which is used by the new coronavirus to reproduce and infect other cells. “We believe that our data and the initial positive results from the PharmaMar clinical trial suggest that plitidepsin should be seriously considered to expand clinical trials of the Covid-19 treatment,” the researchers concluded.
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