US Coronavirus: Leaders in Several States Warn Residents to Be on Guard as Worrying Covid-19 Trends Emerge



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The groups are a “stark reminder” that New Yorkers should be vigilant, Governor Andrew Cuomo said Wednesday.

“Wear a mask, socially at a distance, follow public health guidelines, because this is not over,” Cuomo said in a statement.

Top health officials, including Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, also warned that the US could see an especially challenging fall and winter this year, especially as social settings shift to the indoors during cold weather. They say cities and counties should prepare by keeping safety measures, such as wearing masks and social distancing, in place.

“We are still knee deep in the first wave of this,” Fauci said in a live feed on Facebook and Twitter.

In Kentucky, Gov. Andy Beshear on Wednesday urged the state to halt a recent “spike” in cases after reporting more than 1,000 new infections for the second day in a row.

“Today’s daily report is too high,” said the governor. “I need your help. It’s up to us and we have to do this.”

In Wisconsin, cases and hospitalizations are increasing. The state reported its highest number of Covid-19 hospitalizations on Wednesday, more than double the numbers seen in late August, when they were in the 200s, data from the Covid Tracking Project shows.

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Wisconsin’s seven-day average of daily official new cases peaked Wednesday at 2,334, well above the averages of 600 and 700 seen in late August.

This comes days after the White House coronavirus task force warned Wisconsin of a “rapid worsening” of the pandemic there and urged the state to increase social distancing as much as possible.

And in Illinois, the governor is tightening restrictions in one part of the state after an increase in positivity rates.

As of early Thursday morning, at least 27 states were reporting seven-day averages of new daily cases higher than a week ago, according to data from Johns Hopkins University. Nationwide, more than 7.2 million people have been infected and more than 206,000 have died.

When a vaccine might be available to the U.S. population

On Wednesday, Moderna CEO Stéphane Bancel said that if its Covid-19 vaccine is shown to be safe and effective, it could be available to the general population in late March or early April.

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Moderna began its phase 3 clinical trial for a Covid-19 vaccine in the US in July. It is one of four companies that have started Phase 3 Covid-19 vaccine trials in the US The others are Johnson & Johnson, Pfizer / BioNTech, and AstraZeneca. The AstraZeneca trial was paused internationally after an unexplained illness in a volunteer, and is still on hiatus in the US as US health authorities continue to consider the questions that remain around the experimental vaccine.

“I think a late first quarter and early second quarter approval is a reasonable timeframe, based on what we know about our vaccine,” Bancel told a conference organized by the Financial Times.

But there are several steps that will have to come before that.

If the safety and efficacy data is verified, Bancel says it hopes Moderna will be able to file an Application for Biologics License (BLA) with the US Food and Drug Administration. That application asks the FDA to consider granting a full license to a drug, while an emergency use authorization (EUA) expedites a drug candidate for use in an emergency.

Moderna could apply for an EUA starting November 25 for people who are considered high priority, including healthcare workers and the elderly, Bancel said at a conference organized by the Financial Times.

Until a vaccine is available, experts have long said that the country’s most powerful tools against the pandemic are face masks and other safety measures like social distancing. But even when a vaccine is ready, health officials like Fauci have said there will still be room for the virus to spread, as the vaccine is unlikely to be 100% effective or taken by 100% of the population.

“I think if we can vaccinate 75 to 80% of the population, I think it would be a really good achievement,” Fauci said last week.

Mississippi lifts the mask mandate

Despite officials continuing to advocate for wearing masks, Mississippi Governor Tate Reeves announced Wednesday that he will not extend the state’s mask mandate, saying the state’s figures for the average number of new Covid- 19 have decreased.

“It has been a wonderful few weeks for the Covid-19 numbers,” the governor said. “We have cut our average number of new cases in half, we have reduced hospitalizations by two-thirds of what they were before.”

Mississippi has reported more than 98,000 infections since the start of the pandemic. According to data from Johns Hopkins, Mississippi is one of 14 states that have had a relatively stable track in their number of new cases compared to the previous week.

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More communities across the country have further loosened restrictions in recent days, including in Florida, where the governor led the way for bars and restaurants to reopen completely.

Wyoming, which last week set a single-day record for new Covid-19 cases, also relaxed the rules around restaurants. Nevada relaxed restrictions on public gatherings, while in California, several counties received the green light to move to less restrictive levels of the state’s reopening plan.

Despite removing the masks mandate in Mississippi, the governor urged residents to continue to cover their faces, saying it is “the smartest, most prudent and wisest thing to do.”

CNN’s Kristina Sgueglia, Jason Hanna, Betsy Klein, Lauren Mascarenhas, Claudia Dominguez, and Kay Jones contributed to this report.

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