Fifth The victim was injured and rushed to a local hospital in critical condition, Lt. Jennifer Amat said.
“Police responded to the shooting call at around 5:30 pm and were confronted with gunfire when they arrived at the scene,” Amat told a news conference.
The suspect was rushed to hospital after sustaining gunshot wounds in a shootout with police, Amat said. He said a firearm was found at the scene and the suspicious condition is serious, he said.
The department did not provide any other information about the suspects or the victims.
Orange is located 30 miles south of Los Angeles. The complex where the shooting took place has several businesses, including Farmer Insurance, Calco Financial and Miller Counseling.
It is not clear where the shooting took place in the building.
“I can tell you that we haven’t had an incident like this in Orange City since 1997,” Amat said. “It’s just this kind of tragedy for the victims, their families, our community and our police department.”
News of the mass shooting was immediately condemned.
California Rep. Katie Port said she and her team are monitoring the situation.
The FBI Los Angeles Division confirmed to CNN that it responded to the shooting regularly but the Orange Police Department is the main investigating agency.