Turkey Says China’s Sinovac COVID-19 Vaccine 91.25% Effective In Latest Trials



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ANKARA: A COVID-19 vaccine developed by China’s Sinovac Biotech is 91.25 percent effective, according to interim data from a late-stage trial in Turkey, a potentially far better result than that reported in a separate trial of the vaccine. in Brazil.

Turkish researchers said on Thursday (December 24) that no major side effects were observed during their trial, other than one person having an allergic reaction. Common adverse effects caused by the vaccine were fever, mild pain and mild fatigue, they said.

Researchers in Brazil, which is also conducting a final phase 3 trial of the vaccine, said Wednesday that the injection was more than 50 percent effective, but withheld full results at the company’s request, raising questions. on transparency.

READ: Brazilian institute says CoronaVac efficacy exceeds 50%, but delays full results

The Turkish trials began Sept. 14 and have included more than 7,000 volunteers, the researchers said, adding that the results announced Thursday were based on data from 1,322 people.

Sinovac is the first Chinese vaccine maker to publish details of late-stage clinical trials, following positive results from rival products developed by Pfizer, Moderna and AstraZeneca last month.

The Turkish researchers, speaking together with Health Minister Fahrettin Koca, said that 26 of the 29 people who became infected during the trial received placebos, adding that the trial will continue until 40 people become infected.

“We are now confident that the vaccine is effective and safe (to use) in the Turks,” Koca said, adding that Ankara would use the data to license the vaccine.

He also said that the researchers initially planned to announce the results after 40 people were infected, but that the findings showed that the volunteers had minimal adverse effects after the injection and that it was therefore considered safe.

“Despite being risky, we saw a very clear picture where the COVID-19 PCR test of three people came back positive, with no fever or respiratory problems … We can easily say that despite being risky, those three people passed it very lightly, “he said.

READ: Daily COVID-19 deaths in Turkey at a record 246

SHIPMENTS ARRIVE ON MONDAY

Turkey had agreed to buy 50 million doses of the Sinovac injection and receive delivery by December 11, but the shipment was delayed.

Koca said three million doses would arrive on Monday, adding that Turkey will vaccinate about nine million people in the first group, starting with healthcare workers.

CoronaVac has been administered to tens of thousands of people under an emergency use program that China launched in July targeting specific groups at high risk of infection.

CoronaVac is based on traditional vaccine technology that uses inactivated coronavirus that cannot replicate in human cells to trigger an immune response.

The vaccines developed by Pfizer-BioNTech and Moderna use a new technology called synthetic messenger RNA (mRNA) to activate the immune system against the virus and require much cooler storage.

READ: Pfizer-BioNTech, Moderna and Sinovac: A Look at Three Key COVID-19 Vaccines

The Pfizer treatment is the first fully tested COVID-19 injection to be administered, and it is already being rolled out in Britain and the United States.

Koca said Turkey would sign an agreement with Pfizer-BioNTech for 4.5 million doses of its vaccine to be delivered by the end of March, with the option to purchase another 30 million doses later.

On Thursday, the death toll in Turkey from the coronavirus rose by 254 to 19,115, according to data from the Health Ministry, while the total number of COVID-19 infections increased by 18,102.

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