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Current emerging coronavirus vaccines are designed to be injected into the arm, but researchers say vaccines that are inhaled through the nose or sprayed into the mouth provide increased immunity and protection against viruses, according to a Bloomberg report.
According to the report, most vaccines in human trials require two doses to be effective and their prevention of infection remains uncertain.
Scientists hope to generate superior immune responses from inhaled vaccines that directly target the air cells that the virus invades.
Among the goals of inhalation vaccines is to prevent the pathogen from growing in the nose, which is where the virus can spread to the rest of the body and to other people.
“Local immunization is important,” the report quoted Francis Lund of Alabama State University at Birmingham, who is working with a technology company to produce two nasal vaccines.
Manufacturers of inhaled vaccines rely on some unique characteristics of the lungs, nose and throat, which are lined with the mucous membrane to form a tissue containing high levels of immune proteins that provide better protection against respiratory viruses.
Experts believe that activating these immune weapons can protect the deeper areas of the lungs from damage. It can also improve the chances that vaccines will prevent transmission.
The report said that Michael Diamond, an infectious disease specialist at Washington University in St. Louis, and his team found, in a study in mice in August, that administering an experimental vaccine through the nose created a strong immune response. throughout the body.
The report indicated that vaccines that are sprayed through the nose or inhaled may have other practical benefits. They don’t require needles, may not need to be stored and shipped in cold temperatures, and can reduce the need for healthcare workers to handle them.
The new Corona virus has killed at least 1,139,406 people worldwide since the WHO China office reported the outbreak of the disease in late December, and more than 41,767,540 confirmed infections have been recorded, while at least 28,531,800 people have recovered.
