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Numerous reports of rashes appear in “Covid 19” patients worldwide.
The rash can take many forms: some appear as small red spots, while others appear as flat or raised lesions. Some also have a “hive” appearance, while others resemble a “freeze”.
However, it is too early to say whether these forms of rash are caused by the new coronavirus or are associated with other factors. “This is really a million dollar question,” said Dr. Kannadi Shinkai, professor of dermatology at the University of California, San Francisco, and editor-in-chief of JAMA Dermatology.
In his interview with “Life Science”, Shinkai said: “It is not clear if the skin lesions we see in SK are actually a direct manifestation of the virus on the skin, or if it is a” reaction pattern “due to the intensified response of the immune system Year “.
Shinkai and colleagues wrote in an editorial, published April 30 in the journal JAMA Dermatology, that some rashes can also be caused by complications of the disease or drug reactions, or even due to other viruses in patients with “joint infection” .
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The authors wrote: “Social media posts and online forum discussions have drawn attention to this eruption, but” now is the time for rigorous science. “It takes work to address many unanswered questions, such as how common is the rash, and what does it mean regarding patient end results.
How common is this rash?
Some viral illnesses, such as chickenpox, measles, and hand, foot, and mouth diseases, are known to cause rashes. Shinkai said the virus-associated rash appears more commonly in children. “And that’s why it’s even more surprising” to see numerous reports of rashes in adult patients with Covid 19.
The exact amount of the rash remains unclear. In an early study of more than 1,000 “Covid-19” patients in China, published Feb. 28 in the New England Journal of Medicine, a rash was seen in just 0.2% of patients. However, in a recent study of about 150 hospitalized patients in Italy, it was found that there was a rash in 20% of patients. Shinkai said a study published March 26 in the Journal of the European Academy of Dermatology and Venereology, conducted by dermatologists who “will be able to discover more subtle changes in the skin” than doctors in other disciplines.
Xinkai explained that more studies that follow patients over a period of time are needed to get a better idea of the true spread of the rash associated with “Covid-19”. However, one of the challenges this faces is that some patients may have mild or no symptoms at all, and they may never be diagnosed with Coronavirus.
What does a rash look like?
A characteristic rash can sometimes be a “telltale sign” for a specific infection. An JAMA editorial said it remains to be seen whether this is the case for “Covid-19” patients.
To date, various rashes have been observed in patients with Covid-19. A Spanish study published April 29 in the British Journal of Dermatology classified the crown-associated rash into 5 categories: “macular papular rash,” or one of the characteristics of a viral infection such as measles with red bumps on the skin. . A rash of “urticaria”. A rash with a grid pattern. Also, “vesicular rash” or blistering rash and freezing rash on the toes.
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In addition, a recent report published on April 30 in JAMA Dermatology described the case of a man in Spain who experienced “freckles” or small red spots on the skin. A separate case report, also published in JAMA Dermatology, described a patient in France who had larger injuries.
The timing of symptoms of a covid-19 rash appears to vary greatly, in some cases the rash precedes symptoms such as fever. In other cases, the rash may appear a few days after illness or may not appear late in the course of infection.
Shinkai said research is necessary to conduct a comprehensive evaluation of this rash, and doctors should also examine tissue samples to determine if the virus, known as SARS-CoV-2, can be detected on the skin, and this is the case of some viral diseases causing the rash. Cutaneous
In addition, the importance of these rashes should also be studied, as if they are associated with better or worse results for patients. For example, some patients with skin lesions on the toes have been reported to have mild or asymptomatic cases of corona infection.
Source: life sciences
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