The number of children with “Kawasaki disease” has increased in Europe, what is the relationship with new coronavirus infections? -GIGAZINE



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In European countries like Britain and Italy, there is sudden high fever, swelling of the extremities and abnormal blood vessels.Kawasaki diseaseThe number of children with symptoms of “is increasing” is reported. It appears that some of these children tested positive for the new coronavirus, suggesting that an increase in Kawasaki disease may be associated with the new coronavirus infection (COVID-19). I will do it

Italy and UK explore possible link COVID-19 with childhood inflammatory disease-Reuters
https://www.reuters.com/article/us-health-coronavirus-britain-syndrome/italy-uk-explore-possible-covid-19-link-to-child-inflammatory-disease-idUSKCN2292JM

Coronavirus and Kawasaki disease in children: an intriguing but unproven link
https://theconversation.com/coronavirus-and-kawasaki-disease-in-children-its-an-intriguing-but-unproven-link-137415


Kawasaki disease is a disease that is seen mainly in children younger than 5 years, and rarely occurs in older children, and almost never in adults. He worked at the Central Hospital of the Japanese Red Cross in 1967Kawasaki TomisakuCalled “Kawasaki disease”, as reported by him, it is the most common in Northeast Asia, but has been confirmed in many countries around the world, including Europe. In Japan, between thousands and ten thousand people are affected each year, and there is a trend that there are more boys than girls.

In general, Kawasaki disease is said to cause inflammation of the blood vessels and is said to be caused by excessive activation of immunity. It is not specified whether Kawasaki disease is caused by an infectious disease or an autoimmune disease, and the diagnosis is based on the symptoms presented by the patient. The main symptoms of Kawasaki disease are as follows.

・ Long fever
・ Rash
・ Eye congestion
・ The ends of the limbs turn red and swell firmly
・ Red sores on the lips and tongue (tongue like strawberries), pain and swelling
・ Swelling of the lymph nodes in the neck


In Kawasaki disease, inflammation occurs in the blood vessels of the heart,Coronary arteryDamaged wall of blood vesselsCoronary aneurysm of Kawasaki diseaseThere are severe cases where swelling forms, and sometimes death. Using blood productsImmunoglobulin therapyIt is important in the treatment of Kawasaki disease to prevent hypertrophy of the coronary arteries by performing early treatment.

In general, Kawasaki disease is an acute inflammatory disease that is rarely cured, but patients with severe coronary artery damage are at risk for cardiovascular disease throughout their lives. In this case, it is necessary to reduce the risk of heart attack by taking medications even after adulthood.


During the new coronavirus pandemic, doctors in northern Italy reported an increase in the number of children under the age of 9 with what appears to be Kawasaki disease. Similar cases have been confirmed in European countries such as the United Kingdom, Spain and Portugal, and some of the patients tested positive for the new coronavirus test.

More than a few times more children than usual show symptoms of vasculitis similar to Kawasaki disease,National Health Service (NHS)He has advised doctors to consider the relationship between the new coronavirus and Kawasaki disease. Representing the NHS of EnglandStephen Powis“For children and adolescents, we ask clinical directors across the country to consider the relationship between Kawasaki disease and the new coronavirus as an urgent problem,” he said. He noted that the relationship between the virus and Kawasaki disease is unclear.

In addition, some patients who are severely affected by the new coronavirus infection have been reported to have blood and blood vessel problems.

Patients who become severe due to a new coronavirus infection may have significant problems with “ blood ” – GIGAZINE


Pediatricians have been researching Kawasaki disease for more than 50 years, and it has been pointed out that bacterial and viral infections and carpet cleaners may be the cause. In 2004, 8 out of 11 babies with Kawasaki diseaseNL63It was discovered that a coronavirus calledReportAlthough there are some, this result could not be reproduced in other groups.

It is too early to conclude that infection with the new coronavirus will lead to Kawasaki disease in children, because there are still few details of the case and not all children tested positive for the new coronavirus test. . Furthermore, children who showed symptoms of Kawasaki disease in this case are older than typical Kawasaki disease patients. On the other hand, experts point out that Kawasaki disease may have been caused by an infection with the new coronavirus that weakens the patient’s defense reaction and infection with other bacteria.

Although there are still many unknowns regarding the new coronavirus, “COVID-19 is less likely to become serious in children.The total number of children with Kawasaki disease is small. Still, experts advise parents should take their children to the hospital right away, whether or not they’re in a COVID-19 pandemic, if they show severe symptoms.


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