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Mina Sotaro (provided by himself)
Prime Minister Yoshihide Suga decided to lift the emergency declaration for the new coronavirus in the metropolitan area, and positioned vaccination as the “decisive factor” for the control of the infection. A month has passed since the start of the priority vaccination for medical personnel and the second vaccination is underway. The onset of anaphylaxis, a serious side reaction, has been confirmed, and expectations and anxiety are mixed before inoculation to older people after April. We asked postdoctoral fellow Sotaro Mine (viral immunology) from the US National Research Institute, who completed two vaccines in the United States, about the safety of the vaccine. (Takayoshi Goto)
-In the United States, inoculation is more advanced than in Japan, but are you concerned about secondary reactions?
“The vaccines made by Pfizer, which has started vaccination in Japan, and Moderna, which is seeking approval, tend to have slightly more side reactions like local pain and swelling than other vaccines. Pfizer and Moderna have been targeted by more than 200 millions of times, but no one has been determined to have died or had residual sequelae from the vaccine. ”
-Anaphylaxis, which is a serious side reaction, was also confirmed in Japan.
“It is reported that there were 4.7 out of 1 million cases of anaphylaxis manufactured by Pfizer and 2.5 cases manufactured by Moderna, but it is a type of allergy and can be treated. 93% are 30 minutes after inoculation. Yes you get up on time and get adrenaline pumping fast, you’re on the mend and don’t be too scared. It’s important to watch your progress after hitting. “
-Is there a possibility of secondary reactions after a few years?
“Since live vaccines infect the body, it is possible in principle that the virus of the vaccine strain remains in the body and the latent infectious one is bad. The Pfizer and Moderna vaccines are artificial. We are using RNA, which is the genetic material we did. The mRNA vaccine is
New Corona vaccine sample = provided by Pfizer
With the new technology, it has fewer impurities than conventional vaccines, has a simple structure and is considered highly safe. “
-In your book, you pointed out that vaccination is a large-scale human social experimentation.
“Because it is the first technology in the world to be put into practical use, clinical trials in humans will be carried out after animal experiments. To determine how effective it is in the real world and if herd immunity is established. There is no choice but to conduct human social experiments. Although it may seem a terrifying expression in words, the benefits to be gained compared to certain risks are great, and the light of hope has come to light with vaccines all over the world. world “.
-Did you see any abnormalities after inoculating yourself twice?
“I got the Moderna vaccine and it didn’t hurt when I injected the first and second doses, but when I applied it a second time, my general discomfort became severe the day after the application and I felt like going to work. I was in a state where I could not get it. I felt cold, had pain in the nodules, took a nap, etc. due to the clumsiness of the early stages of a cold or flu. I had a slightly heavier systemic symptom during the day “.
-Is the second inoculation more likely to cause secondary reactions?
“The data shows that there are more side reactions the second time than the first, and they tend to be stronger. People who have already been infected are also more likely to have side reactions. Centers for Disease Control and Prevention (CDC) and state health officials have pointed out that it is best not to go to the same workplace at the same time with mass vaccination, assuming that side reactions will force them to take time off from work. “
-Is it better to inoculate even if there is the possibility of side reactions to some extent?
“It is not unheard of in the world, but it is common in most countries, and vaccines are considered as important as public goods such as water. In rare cases, there is a side reaction, but it is said to be more effective. than that. Even in Japan, accurate information needs to be carefully conveyed and anxiety relieved. “
-What should I do for pregnant women and those who are thinking of becoming pregnant?
“There is no problem for those planning to get pregnant. More than 10,000 pregnant women have been vaccinated in the United States and other countries, but so far no bad things like preterm delivery or miscarriage have happened. Is it really okay? Give birth? There is not much data yet, but it has been pointed out that pregnant women are much more likely to get sick when infected and can affect the fetus. Given the risks, it may be more profitable to hit. “
-Can children get vaccinated?
“Since I had not done a clinical trial for children, I don’t know the safety and efficacy, so I have not succeeded yet. Both Pfizer and Moderna have started clinical trials for children, and the results will be out in a few months. It is believed that it will be possible to get it right from the age of 12. Moderna is conducting clinical trials even under 12 years of age and plans to get it right from the age of zero. ”
Sotaro MineBorn in Kyoto Prefecture in 1981. 39 years old. He graduated from Kyoto University School of Pharmaceutical Sciences, Nagoya University School of Medicine, and completed the Tokyo University School of Medicine. After working at the National Institute of Infectious Diseases, he has held his current position since 2018. Doctor, pharmacist, doctor of medicine. Deputy representative of the management organization “Kobi Navi” submitting information on new coronavirus infections and other information online. He is co-author of “The new crown and vaccines: the uncomfortable truth without knowing.”
