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The president of the Higher Institute of Health, Silvio Brusaferro, during the presentation of the report on the epidemiological situation in the country, clarified that the dying population has a median age of 82 and an average age of 81, adding that 90% of the deceased has more than one pathology, 3 or more in 78% of cases. Furthermore, 39.9% of the deaths were recorded in Lombardy.
Intensive care mainly receives people over 70 years of age and the male population predominates. Conditions (eg, pneumonia, respiratory failure) or symptoms (eg, fever, dyspnea, cough) consistent with SARS-CoV-2 were mentioned in 90.8% of hospitalization diagnoses. In 491 cases (9.2% of cases) the hospitalization diagnosis was not related to infection. In 72 cases, the hospitalization diagnosis referred exclusively to neoplastic pathologies, in 165 cases cardiovascular pathologies (for example acute myocardial infarction-MI, heart failure, stroke), in 70 cases gastrointestinal pathologies (for example cholecystitis, intestinal perforation, obstruction intestinal, cirrhosis), in 184 cases other pathologies.
It is twelve days on average from the onset of symptoms to the observation of the death of the patient. Respiratory failure was the most commonly observed complication in this sample (94.1% of cases), followed by acute kidney injury (23.6%), superinfection (19.3%), and acute myocardial injury ( 10.8%). %).
Antibiotic therapy was commonly used during hospitalization (85.9% of cases), antiviral therapy was used less (50.2%), steroid therapy more rarely (49.8%). The common use of antibiotic therapy may be explained by the presence of superinfections or is compatible with the initiation of empirical therapy in patients with pneumonia, pending laboratory confirmation of SARS-CoV-2. In 1384 cases (24.5%) all 3 therapies were used. 4.1% of SARS-CoV-2 positive deaths received tocilizumab as treatment.
The ISS study on 55,824 deceased elderly people: here the Pdf
