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Everybody vaccinations at the time they are being tested to combat the Sars-Cov-2 virus they are “too much of the same” and, for this reason, could prove ineffective. And only after 4-6 months we may need another vaccine injection because the antibodies “won’t last long.” Not to mention the risks linked to the speed of production to save the world from Covid-19.
If he says it, we must believe it with eyes closed: word of Dr. Robert Rooster, American scientist and luminary who discovered and demonstrated for the first time (between 1983 and 1984) that the cause of AIDS must be attributed to a retrovirus later called HIV. Co-founder and director of the Institute of Human Virology at the University of Maryland School of Medicine and co-founder and chair of the International Scientific Steering Committee of the Global Virus Network, in exclusive a ilGiornale.it He explained to us how the race for the Covid-19 vaccine is progressing. But the news, on many fronts, is not comforting.
There are about 200 investigational vaccines in the world, of which 9 to 10 are already in phase three. What does this mean?
“It means what it says. You don’t have an effective vaccine until you have an effective vaccine: candidates, nothing more and nothing less “.
You are a luminary, you are a scientist who has made sensational discoveries such as the AIDS virus. What is the truth about the Covid vaccine?
“There is a reason some of them are in clinical trials, but my impression is that too many candidates who do the exact same thing. The vast majority of experimental vaccines target the spike protein of the virus in the hope of inducing neutralizing antibodies. This may or may not work. We have a candidate vaccine for other viruses that produces neutralizing antibodies, but these have not been shown to be effective despite the induction of significant amounts of neutralizing antibodies. “
What can you tell us more about these ongoing vaccines?
“As for all the candidate vaccines, we will not know for some time how effective they are or how easy it is to distribute them around the world. We will not know its real safety until months pass and people become infected after being vaccinated. It is still widely premature Predicting the effectiveness of these vaccines and I would be very careful about how the media reports the first announcements without analyzing them with independent experts from the companies. In conclusion, yes, I encourage you to get the vaccine once it is available, but no, I’m not sure this will solve the problem. “
What are the things we don’t know about the Covid-19 vaccine? Is there something “hidden”?
“We don’t know if it will work. We don’t know if it will be safe. We will have to see: these are questions premature. We just don’t know. The candidate vaccines are sensible and valid, but they are too similar and not close enough to be a blueprint and a blueprint in case problems arise. “
A large part of the world’s population is concerned that the need to get vaccinated as soon as possible could cause harmful side effects to the human body. How much is true? Is it okay to be worried?
“We will see. I do not think there will be acute and immediate negative effects. We must see in time if there will be complications in some percentage of people but we will not know until the following months, after a number significant of the people will have been vaccinated. “
What are the risks associated with the speed with which we try to produce the winning vaccine? And what are the benefits?
“The advantages are there speed and the risks are … speed. When you go fast, you don’t get diversity of approaches, we don’t have huge amounts of animal data to know the correlates of protection, but this is a relatively simple virus to vaccinate. Most of the success of a vaccine comes from acute infections like measles, mumps, polio, etc. Everybody Let’s hope in its effectiveness. When you ask the question about speed, you already answer your question: with speed you can arrive earlier and this is positive but in some cases speed can also mean that things have not been well thought out, which is not necessarily this case but still being a thought in my mind. “
An effective vaccine usually takes a few years, this time we could have it within a year of the start of the pandemic. What are the steps that will be “skipped” to speed up production?
“The answer is the same as the previous one.”
Hopefully one or more vaccines will stop Covid-19. But then, how long will the effect of the antibodies last? What do we know about this?
“I don’t think he antibodies They will last a long time. I think they will last less than 6 months, maybe around 4-6 months, I’m saying this based on our past experience with the spike protein, which is similar to other proteins that we have and we don’t have long-lasting antibodies. This is probably a major problem. “
Is this new coronavirus really a natural virus or could it have been “born” in the laboratory? What is the evidence in favor of one or the other thesis?
“There is absolutely no doubt that it is a virus natural. There is no evidence to the contrary. The statements of others who claim otherwise show that they come from people who do not understand the structure of the genome and are trying to cause controversy. “
While waiting for the vaccine, some therapies (like the one administered to President Trump) are being tested with very promising results. What can you tell us about it? Could they even replace the vaccine?
“Definitely the antibodies monoclonal they are a good approach in the early stage of the disease but not in the advanced stage. The problem is to distribute a sufficient quantity of these monoclonal antibodies throughout the world and to use them as often as necessary. This could represent a huge financial and logistical burden, but it is an important advance. “
Italy is one of the nations that has best been able to contain the advance of the virus. What is your opinion?
“You spoke too soon …”
Are masks and spacing the only weapons we have to contain the spread of infection or can we do more?
“One lucky thing about Italy, especially in the center and south, is that you can spend a lot of time in the air open. We should be outdoors as much as possible. Certainly, you should not enter environments with large groups of people. “
You are one of the scientists who discovered the HIV virus and for that the world will always be grateful to you. Now it is less scary because there are effective treatments, but will the war against AIDS finally be won? Are there new drugs and trials in progress?
“Thanks, I’m always there new HIV drugs are coming to see if we can establish a functional cure. “
