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«The latest figure speaks of 580 deaths in 24 hours. Try to imagine what will happen, at this rate, in January-February, when the first doses of the vaccine. What expectations will there be? To organize the distribution, the Army will be needed, there will be a security problem, because there will be a race to protect itself with the vaccine. Talk is a source close to the government. See what can happen when, in the first months of 2021 (as confirmed yesterday by Professor Franco Locatelli of the Scientific Technical Committee) the first doses of the anti COVID-19. Surveys reveal the distrust of Italians towards this tool, but it is one thing to hesitate to get vaccinated against the flu, another to have the possibility of immunizing against a disease that kills 500 to 600 people every day and sends them to intensive care. 200-300 (this could be the scenario in January).
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We need, and we need immediately because 2020 is ending, a plan that recruits staff, decides which structures are used, which buildings, which cold rooms, how many people will be vaccinated every day, who should do it first and who should do it second. Does it make sense to prepare the organizing machine, since there is no approved vaccine yet? Yes, because production has started and countries like the UK and Germany are already getting organized. “We have to start as soon as possible with a plan – says Agostino Miozzo, coordinator of the CTS – because vaccinating millions of people in a few months is an operation that was never carried out.”
Understand: for the flu vaccine, the organizational machine is already in crisis and only 16 million doses are discussed. But against SARS-CoV-2 the vaccines to be administered will be triple. With unprecedented logistical difficulties, because one of the vaccinations incoming (Pfizer-BioNTech) should be stored below minus 70 degrees. The BBC explains about the UK: ‘Health Secretary Matt Hancock spoke of the’ gigantic logistical operation ‘of transporting the Pfizer-BioNTech vaccine from the point of manufacture to the patient’s arm. It cannot be removed from a temperature of -70 degrees more than four times. And that temperature is about four times colder than the average freezer. ” It will be distributed by land and air by logistics centers in Germany, Belgium and the USA.
Once the vaccine you cannot wait more than five hours. Different speech for the other vaccine, very promising, for which phase 3 will end in two or three weeks and authorization could arrive in January: this is what unites Oxford, Irbm and AstraZeneca. It can be stored in a normal refrigerator, therefore with less logistical problems. Well then, what vaccine will the Italians be given? To date, we should answer: we do not know.
None of the 9 phase 3 vaccines (including Pfizer and AstraZeneca) have been validated by regulatory authorities. In practice, Italy is likely to use the two most promising, Pfizer and AstraZeneca. If there is already an agreement for the second, signed on time that allocates 70 million doses to Italy, for Pfizer’s, the European Union will sign today a contract for a first batch of 200 million (but in the end it will be 300); 27 million doses for Italy. From an organizational point of view, AstraZeneca could be used in areas where sophisticated storage facilities like those required for Pfizer vaccine cannot be guaranteed. At what point is the Italian plan? “There is a working group formed on November 4 with 15 experts – they explain to the Ministry of Health – who will have to deal with the entire plan, from transportation to storage, until the arrival of the doctors who will administer it.”
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