English variant of the coronavirus, Moderna and Pfizer are testing vaccines to verify their effectiveness. Biontech: “It is very likely that it will work”



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Virologists and immunologists hypothesize that the English variant of Sars Cov 2 does not affect vaccines developed to curb the pandemic, but in any case to avoid surprises and to intervene – once a vaccine is “designed” it can be changed as occurs every year by the influence – Modern me Pfizer-Biontech they are testing their compounds in the new variant found in the UK, as CNN reports. “Based on the data to date, we hope that the immunity induced by the Moderna vaccine will protect against variants recently screened in the UK; We will conduct further tests in the coming weeks to confirm this expectation.“Moderna says in a note. Pfizer said it is now” processing data “on blood samples from people immunized with its vaccine to see if it is” capable of neutralizing the new UK strain “, as all experts hope.

The variant that appeared on Gan Britain “is a bit different” from those considered so far, “and we still don’t know exactly if our vaccine can protect against this as well. However, from a scientific point of view, it is very likely that our vaccine can also defend against this variant, “said the founder of Biontech. Ugur Sahin, at a press conference. Now it will take two weeks to collect data on this, he also stressed. An adaptation of the vaccine to the new variant of the virus that appeared in Great Britain ‘”would last six weeks“However, the procedure to obtain authorization would require additional time, he also clarified. Sahin said that from a scientific point of view it is highly probable that the vaccine authorized yesterday by the EMA and the EU could also have an effect against the mutation.

Waiting for certain data, obtained from specific laboratory analysis, as you will remember Giorgio Palù, virologist and new president of Aifa. not done at this time “Any virology experiment on the strength and damage that the virus can produce, nor are there clinical data to show that it is more aggressive or less. This variant has been found in more than 1600 sequenced genomes and appears to be the one currently circulating the most in England. “The data on this new variant, unpublished” in a scientific journal, indicates that it was already found in September in Kent, and then extends to London, Oxford, Glasgow, Scotland, South Africa, Denmark and the Netherlands – continues – It is a highly mutated strain (at least 17 mutations and 9 in protein S), which now seems to prevail in circulationHowever, based on current data, it cannot be absolutely said that this variant causes the virus to be it is also not true and proven that the clinical course of the infection has changed. In fact, preliminary data seem to indicate that those who have been vaccinated have antibodies capable of neutralizing this strain as well ”.

Among the hypotheses formulated about the origin of this variant, it is found that “who was born in immunosuppressed subjects, in whom there are no defenses, viruses grow faster and mutate fasterPalù continues. However, we must not forget, concludes the expert, that “already in spring-summer, compared to the Wuhan virus, the D614 mutation occurred, again in the S gene, which made the virus more infectious. Now, even for the English variant, it will be necessary to carry out all the experiments that have not yet been carried out, using human cells, organoids, experimental animals and antibodies that neutralize the virus ”.



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