Covid vaccine, from effectiveness to who should do it and how much it costs: 35 questions and answers from AIFA



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The first 9,750 doses of vaccine Pfizer-BioNTech are in Rome. Starting today, December 26, they will be available at Spallanzani. And tomorrow will be Vaccine Day, the date on which the first doses of the vaccine will be symbolically administered. anti-Covid Across Europe. What is there to know about the vaccine? L ‘Aifa, the Italian Medicines Agency, gives answers to questions through the Frequently asked questions.


Vaccino, the first doses at Spallanzani: tomorrow V-Day in Italy (and throughout Europe)

The questions

The AIFA document answers 35 questions: from the operation to the population to which it will be administered. Here are some of the top questions and related clarifications (full list in attachment)

What is it and what is it for? The COVID-19 mRNA BNT162b2 vaccine (Comirnaty) is a vaccine intended to prevent coronavirus disease 2019 (COVID-19) in people 16 years of age and older. It contains a molecule called messenger RNA (mRNA) with instructions for making a protein found in SARSCoV-2, the virus responsible for COVID-19. The vaccine does not contain the virus and cannot cause disease.

How effective is it? The results of these studies showed that two doses of the COVID-19 mRNA BNT162b2 vaccine (Comirnaty) administered 21 days apart can prevent 95% of adults over the age of 16 from developing COVID-19 with substantially age-homogeneous results, gender and ethnicity. The 95% reduction refers to the difference between the 162 cases that occurred in the group of more than 18,000 who received the placebo and the only 8 cases that occurred in the more than 18,000 who received the vaccine.

How long does the protection induced by the vaccine last? The duration of protection is not yet defined with certainty because the observation period was necessarily a few months, but knowledge about other types of coronavirus indicates that protection should be at least 9-12 months.

Can vaccinated people transmit the infection to other people? The clinical studies carried out so far have made it possible to evaluate the efficacy of the COVID-19 mRNA BNT162b2 vaccine (Comirnaty) in clinically manifest forms of COVID-19, and more time is needed to obtain meaningful data to demonstrate whether vaccinated individuals can become asymptomatically infected. and infect other people. While it is plausible that vaccination protects against infection, vaccinated people and those in contact with them should continue to take protective measures against COVID-19.

What adverse reactions have been observed? The most commonly observed adverse reactions (more than 1 in 10 people) in the COVID-19 mRNA BNT162b2 vaccine study (Comirnaty) were generally mild or moderate in severity and resolved within a few days of vaccination. These included pain and swelling at the injection site, fatigue, headache, muscle and joint pain, chills, and fever. Fewer than 1 in 10 people experienced redness and nausea at the injection site. Itching at the injection site, pain in the extremities, swollen lymph nodes, difficulty falling asleep and nausea were rare and affected less than 1 in 100 people. one side of the face (acute peripheral facial paralysis) has occurred rarely, in less than 1 in 1000 people.

Anyone who has already had a confirmed COVID-19 infection should or can get vaccinated? Vaccination does not contrast with a previous COVID-19 infection, but rather improves your immune memory, so no pre-vaccination test is helpful. However, those diagnosed with positive COVID-19 do not need vaccination in the first phase 5 of the vaccination campaign, although it could be considered when data are obtained on the duration of immunological protection.

Who should I contact to get vaccinated? The vaccination campaign will be carried out in several successive phases, the public will be invited to carry out the vaccination in an order of priority defined by the risk of people becoming infected and developing the disease with serious consequences. In the initial phase, the vaccination will be reserved for health personnel and staff and guests of nursing homes and vaccinations will be carried out by the staff of the vaccination services in the 286 hospitals defined by the National COVID-19 Vaccination Plan. The same vaccination staff will go to nursing homes for vaccination.

How much does vaccination cost? Vaccination is free for everyone.

What documents are required to carry out the vaccination? A valid identity document and a health card. It may also be helpful to carry any health documentation with you that can help the vaccinator assess physical status.

Last updated: 13:20 © REPRODUCTION RESERVED



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