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London alarm for a new variant of SarsCov2. British Prime Minister Boris johnson announced a harsh blockade for the English capital which was justified at the press conference by the discovery of this new strain of coronavirus that would be 70% more contagious of that hitherto unknown. He spoke on the subject in a long thread on Twitter. Giorgio gilestro, neurobiologist and associate professor ofImperial College London.
‘The virus appears to be circulating faster due to a new variant, there is no evidence of an increase in lethality, but it seems to be spreading faster. That’s all we know, but we have to act now. “. He said Boris johnson At the press conference. “Nothing at the moment indicates that the vaccine will be less effective”he added.
“Last week, Johnson announced no major changes to the December closings during the Christmas holidays, with openings on Christmas days allowing up to three families to reunite. This new variant is changing the cards on the table – wrote Gilestro in the first of his tweets about it – Now it seems that a new level of closure (level 4) will be introduced and that London and the Southwest will return to stay home, as in March, without even the gaps in Italian tarallucci and wine announced yesterday by Conte. “.
“The reason – Gilestro adds – would be a variant of the virus described in this prepress. More than a variant, it is a family of variants with something in common: a deletion of two amino acids at position 69/70 and a series of polymorphisms in RBD. All mutations refer to the exposed region of the peak protein, that is, the parts recognized by the antibodies. I probably am Successful attempts by the viral strain to escape the antibodies of those who have developed immunity and are immune, for example, to plasma therapy.. Phylogenetically speaking, the 69/70 deletion developed in a branch that contained the 453 mutation – already known in the chronicles as the one isolated in Danish ferrets that led to its extermination for reasons of precaution».
“At the moment – emphasizes the expert – There is no evidence that these new strains are more lethal but it is clear that they are more virulent. England immediately informed WHO. What does that mean? This is not good news. These are strains that have developed under evolutionary pressure: It means that as soon as a sufficient number of people begin to have antibodies against the virus by directly acquired immunity or by vaccination, new strains emerge.».
“They are logs – Gilestro adds – that manage to escape the antibody response and therefore they behave like a new virus. The bad news is that the virus has a strong rate of evolution. The good news does not come to mind at this time but I should add it below “.
“In summary – Gilestro explains in his thread – the variant is now the main variant in circulation (we have a “new virus” in London); up to 70% more contagious; Londra on level 4; It is strongly recommended not to leave the country.; we don’t know if the variant is already outside the UK or where it came from. Given the contagion, given the number of EU immigrants in London, given the period (Christmas), I am afraid that it is now taken for granted that this variant will spread rapidly to the rest of Europe.».
And in possible consequences related to the vaccine conclude: “To everyone who asks ‘does that mean the vaccine won’t work?’ There is currently no evidence that this variant is immune to the vaccine.. Its effectiveness may change. It is necessary to monitor cases of reinfection. If we see that the number of reinfections increases drastically, we must begin to fear that this generation of vaccines is not as effective as we hope.. Fortunately, with this new mRNA technology, new vaccine variants are rapidly being produced.».
Last updated: 20:27 © REPRODUCTION RESERVED
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