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A 90-year-old woman from Northern Ireland who was the first person in the world to be administered the Pfizer / BioNTech vaccine against Covid. This is Margaret Keenan, who will turn 91 in a few days: it means that with the new year she will be able to see family and friends after spending most of this year alone, the lady said. But how long will it really takeFor you and for all those who will soon be vaccinated against Covid to finally be safe?
Strong protection already after the first dose.
The manufacturer stated that the vaccine is administered in two doses at a range of three weeks of each other and that the efficacy of vaccination is achieved after 7 days from the second dose. Ugur Sahin, CEO and co-founder of BioNTech, also said: The study (Phase 3, ed) indicates that a high rate of protection against Covid can be achieved very quickly already after the first dose. A document published by the Food and Drug Administration USA, according to New York Times, talk about a strong immune response in the first 10 days after the administration of the first dose. The FDA released a detailed analysis of the Pfizer / BioNTech vaccine today (Tuesday morning) ahead of a meeting Thursday of a group of independent experts who will advise the agency. whether or not to grant permission emergency use of the vaccine. The agency’s analysis essentially confirms the manufacturer’s study data, noting that no specific safety issues have been identified and confirming a strong protection even after the first dose. The vaccine has been deemed safe and effective, two requirements that lead to the belief that there will be official approval on Thursday.
Protected two weeks after the second dose, usually
However, for full safety, vaccinated people would do well to protect themselves for up to a week or two after the second dose, then about a month after the first inoculation. Protection takes weeks: the immune response takes time to “mature” and be optimal, he explains. Sergio Abrignani, Immunologist at the State University of Milan and the Institute of Molecular Genetics “Romeo and Enrica Invernizzi” -. It usually takes two weeks after the second injection. have a good level of protection. Since we have been racing against time to come up with the vaccine, some details will come after more studies, more definitively. For now we assume that the Pfizer vaccine also behaves like everyone else, as it seems, because they saw that the protection developed a few weeks after the second dose. We always talk about protection against disease.
Form attenuated even for 5% not covered
The effectiveness of the vaccine reaches 95%, a high figure, if we take into account that the flu reaches 40-60%. And that 5% of people who will not be protected? In all vaccines, 100 percent does not exist and someone will not be protected – Abrignani clarifies -. Who vaccinated him, because, if he got Covid-19, would make the disease attenuated. Pfizer said that those 7-8 patients, who became infected in the Phase 3 efficacy studies despite the vaccine (compared to 162 who received placebo), did not have severe disease. This confirms what also applies to the flu: people who get sick anyway avoid the worst complications.
To Italy 27 million doses after authorization
Europe has already secured its share of the vaccine thanks to a contract signed on November 10 with Pfizer and BioNTech. fourth after those signed with AstraZeneca, Sanofi-Gsk and Johnson & Johnson. The agreement, announced by Ursula von der Leyen, President of the European Commission, consists of two parts: the first for the supply of 200 million doses, to which you can add an option for another 100 million, assigned with criteria to be established. The quota reserved for Italy, for now relative to the first tranche, 13.51% of the total, or 27 million doses. The distribution is based on the population of each Member State in relation to the total population of the EU.
December 8, 2020 (change December 8, 2020 | 15:57)
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