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1 – Will the mutation lead to other closures?
“The current situation implies a strengthening of diagnostic measures (more expensive tests because they are based on sophisticated technologies), fundamental tests to understand where the English variant circulates, in order to properly manage the control of the diffusion. However, it will be necessary to maintain strict preventive measures. hitherto adopted rather than loosening them. “This was stated by Professor Marco Tinelli, an infectious disease specialist at Simit:” Until we have adequate vaccination coverage of at least 70% of the population (the six types of vaccines that will arrive in Italy will also work with this variant), the virus will continue to circulate and will be able to infect “.
Peak mutations have been identified in several locations: deletion 69-70, 144, N501Y (the major one), A570D, D614G, P681H, T716I, S982A, D1118H. “This new variant differs in transmissibility much greater than, according to the recent report of the European Infectious Diseases Control (ECDC) is equal to + 70%.
2 – Asymptomatic increasing with the variant?
The percentage of asymptomatic people in Covid-19 caused by the English mutation has not yet been quantified. The risk is that this variant, much more contagious, could cause a significant increase in both contagious asymptomatic cases and the real ones of Covid-19 in full rule. Sars-CoV-2 is an RNA virus that, unlike others, has the characteristic of mutating more frequently, and since the first isolation in China it has already had 3 main mutations. The new variant (the fourth) isolated in Great Britain has again modified the spike proteins of the virus that allow it to adhere to human cells to infect them.
3 – Face-to-face classes from January 7?
It is difficult for schools to predict whether lessons will be able to restart in the new year in physical mode with teachers and students in the classroom. “Under these conditions – states Walter Ricciardi, councilor for the Ministry of Health – it is difficult to think of reopening the school in the presence of January 7”. Whatever happens, it will be very important, at the time of departure, to avoid the crowds in public transport, along the transport network (with the races already reduced) and the crowds inside and in front of the entrance from schools.
4 – Does this virus cause more damage to the body?
“This virus, in the English variant, now spreads more easily. However, this does not mean that it causes more damage to the organism that hosts it than before, because doing so would end up becoming extinct. I would say that indeed, the virus points to reproduce., trying to coexist with the human organism that harbors it. ”This was stated by virologist Carlo Federico Perno, UniCamillus university professor and director of Microbiology at the Bambino Gesù Pediatric Hospital in Rome. Gupta of University College London, where the new variant has been isolated.
5 – Will the tests and vaccines be valid in the variants?
Laboratories will need to update nucleotides and reagents so that they have reliable molecular swabs and specific rapid antigenic tests that can also diagnose the English variant of the virus, which has undergone three mutations from the previously circulating version. However, it should be noted that this virus is not more aggressive than previous coronaviruses. As for the fears that the English variant could frustrate the anti-Covid vaccination campaign, do not panic – explains Maria Rita Gismondo, director of the Laboratory of Clinical Microbiology, Virology and Diagnostics of the Sacco hospital in Milan – since currently targets are developing Stimulated antibodies are many, there should be no substantial problems. All available or upcoming vaccines aim to induce the production of neutralizing antibodies against the spike protein, taking advantage of a mosaic of antigens, thus achieving multiple goals.
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