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Harianjogja.com, JOGJA– The coronavirus is said to have mutated in the DIY and Central Java regions. A D614G mutation of the SARS-CoV-2 corona virus was detected in the Yogyakarta Special Region (DIY) and Central Java (Central Java).
The findings were revealed after the Genetic Working Group of the Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada (FK-KMK UGM) and the team managed to identify the whole genome sequencing (WGS) of four isolates from Yogyakarta and Central Java, which have been published in GISAID.
Three of the four isolates contained the D614G mutation.
The chairman of the FK-KMK UGM Genetic Working Group, Dr. Gunadi, revealed that the D614G mutation in the SARS-CoV-2 virus has a 10 times higher infectious power.
The D614G mutation, Dr. Gunadi said, had spread to almost every corner of the world, specifically 77.5% of the total 92,090 isolates containing the D614G mutation.
He added that in Indonesia alone, nine of the 24 isolates published in GISAID had been reported to contain the D614G mutation.
“One third was detected in Yogyakarta and Central Java,” Dr. Gunadi said on Tuesday (1/9/2020).
Dr Gunadi admitted that the Indonesian data is still far from ideal compared to the global data in benefit of data on the spread of the virus in the population (epidemiology) and the development of COVID-19 vaccines and / or therapies in the world, especially in Indonesia.
Even so, he continued, with the fact that the D614G mutation of the SARS-CoV-2 virus was detected in Indonesia, all parties should be more disciplined in implementing health protocols, such as washing hands, wearing masks, avoiding crowds. , etc.
To date, the total COVID-19 infected population worldwide is 25,590,934 cases, with a death rate of 853,415 cases.
Meanwhile, in Indonesia itself, since the announcement of the first COVID-19 patient in March 2020, as of August 31, 2020 there were 174,796 cases of COVID-19 with 7,417 patients dying.
The case data puts Indonesia in 23rd place with the most patients in the world.
On the other hand, unfortunately, Indonesia’s SARS-CoV-2 WGS data published in GISAID is very minimal, that is, 24 complete genomes compared to 92,090 complete genomes from around the world (September 1, 2020).
In fact, WGS data are very important in understanding the epidemiology (spread) of the virus, including the type of mutation (clade) in the community, its relationship to the severity of COVID-19 patients, vaccine development, and / or therapy for COVID-19 in the future, especially in Indonesia.
“So the WGS data of Indonesian isolates is a necessity and a form of independence for Indonesian national identity,” said Dr. Gunadi.
Source: Suara.com
