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Jakarta, CNBC Indonesia – Researchers from the National Institute of Allergies and Infectious Diseases (NIAID) found that Moderna’s Covid-19 vaccine was successful in producing strong antibodies that last at least 3 months to combat Covid-19.
This NIAID study was conducted by studying the immunity of 34 adult participants, young and old, from a first-stage clinical trial. The results of this study were published in the New England Journal of Medicine on Thursday (3/12/2020).
The researchers revealed that the antibodies that prevented the SARS-CoV-2 virus from attacking human cells “decreased gradually over time, as predicted, but continued to increase in all participants 3 months after the booster shot,” they said. researchers. Researchers as cited by AFP, Saturday (12/5/2020).
Although the amount of antibodies in the study subjects decreased over time, it is still not a cause for concern. The vaccine is injected 28 days apart.
NIAID Director Anthony Fauci and other experts said the immune system is very likely to remember the virus if it is later exposed again and then produces new antibodies.
Fortunately, research suggests that the vaccine activates certain types of immune cells that should aid in the so-called memory response, but only long-term research will determine if this is indeed the case.
“The positive aspects of this study include evidence that a relatively strong antibody response persists 90 days after the second dose of vaccine,” said virologist Benjamin Neuman, a virologist at Texas A & M University-Texarkana.
“The amount of antibodies produced by the vaccine is higher in younger patients than in older patients, but a fairly strong immune response is still seen even in patients up to 70 years old.”
The Moderna vaccine will be reviewed by the Food and Drug Administration (FDA) advisory committee on December 17, and may turn green for emergency approval shortly thereafter.
Like other vaccines made by Pfizer and BioNTech, this vaccine is based on a new technology that uses genetic material in the form of mRNA (messenger ribonucleic acid).
The mRNA is wrapped in a lipid molecule and injected into the arm, where it causes the cells in our muscles to accumulate the coronavirus surface protein.
This tricks the immune system into thinking it has been infected with microbes and trains it to build up the correct type of antibody when it encounters the real virus.
[Gambas:Video CNBC]
(Roy / Roy)