Judging by the differences between the Oxford-AstraZeneca and Pfizer / BioNTech vaccine, what are they? All pages

KOMPAS.com – Great Britain announced that it will be the first country in the world to approve the Covid-19 vaccine manufactured by the University of Oxford-AstraZeneca on Wednesday (12/30/2020).

This action is in addition to the supply of aid injections of the Covid-19 vaccine to combat the corona virus pandemic.

Previously, the UK also approved the use of the Pfizer / BioNTech vaccine for use in their country.

Also read: Profile of AstraZeneca, supplier of 100 million Corona vaccines for Indonesia

So what are the differences between the Oxford-AstraZeneca and Pfizer / BioNTech vaccine?

Vaccine effectiveness

Reporting from Reuters (12/31/2020), according to interim data, the AstraZeneca / Oxford corona virus vaccine is said to be effective in preventing symptomatic Covid-19 infection with an efficacy level of 70.4 percent.

This figure was obtained from 5,807 people who received the two-dose vaccine after 30 days, compared with 101 of 5,829 people who received a placebo.

That compares with the 95 percent efficacy of the Pfizer / BioNTech two-shot vaccine.

However, those who received half the dose of AstraZeneca vaccine, followed by the full dose, were shown to have 90 percent protection.

Also read: The efficacy of the Sinovac vaccine is different in various countries, how can it be?

Technology, pricing and storage

Regarding costs, AstraZeneca promised that the vaccine costs only a few dollars per dose and is sold at no profit, while Pfizer’s vaccine costs between US $ 18.40 and 19.50 or around Rp.

For vaccine storage, AstraZeneca does not require freezing at temperatures of minus 70 degrees, however this vaccine can be stored in a standard refrigerator for 6 months.

The standard refrigerator temperature ranges from 2 to 8 degrees Celsius.

Meanwhile, the Pfizer / BioNTech vaccine should be stored in a refrigerator with a temperature of minus 70 degrees Celsius.

Also read: Explanation of the Ministry of Health on Vaccination by SMS that begins to be sent today

Manufacture of vaccines

According to the news Kompas.com (20/11/2020), AstraZeneca is based on the chimpanzee adenovirus, which is modified to produce a protein in human cells that is also produced by Covid-19.

That is, the viral vector vaccine is made from an attenuated version of the common cold virus that causes infection in chimpanzees.

The chimpanzee flu virus has been genetically altered to include genetic sequences for so-called proteins. spike which is used by the corona virus to enter human cells.

Also Read: Crowded Questions About Suspicious PCR Test Results For Free Sale, Here’s The Explanation …

Meanwhile, Pfizer and BioNTech are using the latest technology based on a synthetic version of the SARS-Cov-2 virus molecule called “messenger RNA,” or mRNA for short.

So far no vaccine based on this technology has been officially licensed.

Vaccines produced with this latest technology are like hacking human cells and effectively transforming them into a “vaccine manufacturing factory.”

Another advantage of this technology is that vaccine production is much faster than conventional vaccine manufacturing technology.

Also Read: Many Topics About Quick Antigen, Is It Similar To An Antigen Swab?

KOMPAS.com/Akbar Bhayu Tamtomo
infographics: different antigen test, rapid antibody test and PCR