Serum Vaccine in Phase I / II Trials in Australia


By: Desk Explained | Pune |

Updated: September 25, 2020 11:49:27 am


coronavirus, coronavirus vaccine, corona vaccine, serum institute vaccine, indian covid 19 vaccine, indian coronavirus vaccinePeople wearing face masks walk past an outdoor photo exhibit of healthcare workers in Melbourne, Tuesday, Sept. 22, 2020 (James Ross / AAP Image via AP)

Coronavirus Vaccine Tracker: In addition to bringing some of the top contenders for a coronavirus vaccine to India, the Serum Institute is also developing its own vaccine. It is partnering with SpyBiotech, a spin-off from the University of Oxford, for this purpose. Your vaccine candidate has entered combined phase I / phase II clinical trials, which are underway in Australia. The trials began in the first week of September.

Serum is also licensed to produce and market two of the main candidate vaccines, one developed by AstraZeneca and the University of Oxford, and the other by the American company Novavax. The Oxford University vaccine is currently in phase II and phase II trials in India.

New York State says it will review any vaccine approved by the US federal government.

Further politicizing the coronavirus vaccine debate, New York Gov. Andrew Cuomo said Thursday that his state would review any federally approved vaccine before approving it for public use. Cuomo said this was due to fears that the federal government could rush to approve a vaccine for political reasons without due regard for its safety or efficacy.

“Frankly, I am not going to trust the opinion of the federal government, and I would not recommend New Yorkers, based on the opinion of the federal government,” Cuomo said in a New York Times report.

“Unfortunately, we can no longer trust the federal government,” he said.

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The coronavirus vaccine has been at the center of intense speculation and debate in the United States ahead of the November 3 presidential election. When most companies and experts said that a vaccine would not be available before the beginning of next year, the President of the United States, Donald Trump, insisted. which could be ready later this year. Later, he said the vaccine could also be available before the election date. Since then, the schedule for vaccines, at least for their availability in the United States, has been pushed forward to the end of this year.

As of now, four leading vaccine candidates, those from AstraZeneca, Moderna, Pfizer, and Johnson and Johnson, are in phase 3 clinical trials in the United States. Pfizer has said that it expects to know by October whether its vaccine candidate is effective or not. If the trials yield satisfactory data, the company has said it would immediately apply for an emergency authorization to make it available to the public. Other vaccine candidates are expected to know their effectiveness data in December or January of next year.

Search for the coronavirus vaccine: the story so far

  • 187 candidate vaccines in clinical or preclinical trials
  • 38 of them in clinical trials
  • Nine in the final stages, phase III human trials
  • At least eight potential vaccines are under development in India. Two of them have entered phase II trials after completing phase I.

The most commented:

* AstraZeneca / University of Oxford
* Modern
* Pfizer / BioNTech
* Johnson and Johnson
* Sanofi / GlaxoSmithKline
* Novavax
* Russian vaccine, developed by Gamaleya Insttiute in Moscow
* Three Chinese vaccines that have been approved for use in China without completion of phase 3 trials. One of them has received emergency use authorization in the UAE

(As of Sept 23; source: WHO Coronavirus Vaccine Overview Sept 22, 2020)

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