It will take until 2024 to vaccinate the whole world, said Adar Poonawalla (Representative)
The world’s largest vaccine maker is ramping up production of AstraZeneca’s Covid-19 injection, aiming to have 100 million doses ready by December for an inoculation campaign that could begin across India later that month.
If end-stage trial data shows AstraZeneca’s candidate provides effective protection against the virus, the Serum Institute of India, which partnered to produce at least 1 billion doses, could get an emergency clearance from New Delhi. in December, said Adar Poonawalla, director. CEO of the Pune-based family business.
That initial amount will go to India, Poonawalla said in an interview Thursday. Full approval early next year will allow distribution on a 50-50 basis with the South Asian nation and Covax, the World Health Organization-backed body that is buying injections for poor nations.
Serum, which has partnered with five developers, has so far manufactured 40 million doses of AstraZeneca’s vaccine in the past two months and aims to start manufacturing the Novavax competitor soon.
“We were a little concerned that it was a big risk,” said Poonawalla, 39. But the AstraZeneca and Novavax shots “look pretty good.”
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The rush underscores Poonawalla’s confidence in one of the leading vaccine pioneers. AstraZeneca CEO Pascal Soriot has said that he is bracing for the possibility of large-scale vaccines starting in December and once the UK grants its own emergency license, Serum will send that same data to its Indian counterparts. .
Drug makers are only now getting data that will show how well their vaccine candidates work, but many hurdles remain as the global race to find an effective vaccine against the pathogen reaches its final stages. Astra and the Oxford University co-developer still need to see the test results. And even if your vaccine is effective and gets the go-ahead from regulators, there are questions about how easily and quickly the injection can be delivered.
Poonawalla reiterated that it will take until 2024 to vaccinate everyone and two years to see a real reduction in infections, due to affordability and manufacturing hurdles.
After speaking with the government, Poonawalla said she is confident in their plans to bring the initial vaccines to front-line and vulnerable workers. The challenge will be to bring it to India’s 1.3 billion population, especially in the vast countryside where past vaccination campaigns have struggled due to spotty healthcare networks.
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He said AstraZeneca has a significant advantage over a rival candidate from Pfizer and BioNTech SE, which this week made headlines after stating it was more than 90% effective in stopping Covid-19 infections. An expensive cold chain infrastructure is needed to transport and store that vaccine at -70 degrees Celsius. Poonawalla said it was “simply impossible” for most of the world to use them on a large scale, compared to what his company will produce and which can be stored at refrigerator temperatures.
“I don’t think even 90% of countries can accept it, because there are just no freezers everywhere,” he said of the Pfizer injection. “In a pandemic, always remember that simplicity is the key.”
For India, which has struggled to contain the world’s second-largest Covid outbreak, negotiations with the Serum Institute on the price of vaccines will be critical to the country’s efforts to emerge from the pandemic.
India said it will keep $ 7 billion ready for the vaccine at $ 2 per injection
India has set aside about 500 billion rupees ($ 6.7 billion) for vaccines, people with knowledge of the matter said last month. However, in September, Poonawalla argued that India would need 800 billion rupees. Poonawalla declined to comment further.
Fast question; Will the government of India have Rs 80 billion available next year? Because that’s what @MoHFW_INDIA need, buy and distribute the vaccine to everyone in India. This is the next worrying challenge we must tackle. @PMOIndia
– Adar Poonawalla (@adarpoonawalla) September 26, 2020
Poonawalla is making a big financial gamble. Operating in the world of low-margin, mass-volume vaccines, the Serum Institute, founded in 1966 by Poonawalla’s billionaire father, Cyrus, supplies 170 countries with more than 1 billion vaccines a year for diseases such as measles and mumps. .
About $ 300 million of the company’s money has been invested in initial production, Poonawalla said. The Bill and Melinda Gates Foundation and Gavi, the vaccine alliance, have also contributed $ 300 million this year, allocating 200 million doses to the Covax effort. That leaves around $ 200 million to cover Serum’s planned expenses.
Poonawalla said fundraising talks with the sovereign wealth funds of Abu Dhabi and Saudi Arabia along with the US private equity firm TPG Capital are now “on hold”, although they could be reviewed in a couple of months. Although the parties came close to reaching an agreement, Serum’s plan to price its Covid-19 vaccines at a low level may not give them the benefits they hope for, he said.
“All of them wanted to give us between $ 1.5 and 2 billion to dilute a stake in our company; I don’t need it all now, the capital we have already deployed is enough,” Poonawalla said, adding that advance. recently signed orders with countries like Bangladesh should fill the gap. Serum is also in talks with India for an early engagement. “I think in the next month or two I will be fully capitalized.”
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