Coronavirus India LIVE Updates: Rapid tests for Covid-19 take place in Mumbai on Tuesday. (Express photo by Amit Chakravarty)
Coronavirus India LIVE updates
The Central Drug Standard Control Organization (CDSCO), which published a new set of guidelines for Covid-19 vaccines on Monday, also emphasized that the statistical range of efficacy (the ability to produce the desired result) in human trials it cannot be less than 30 percent.
The guidelines come several months after the World Health Organization (WHO) and the U.S. Food and Drug Administration (FDA) published their own guidelines for Covid-19 vaccine approvals and are based on both documents, according to experts who have been closely following and involved in the development of the Covid-19 vaccine.
“To ensure that a widely implemented Covid-19 vaccine is effective, the primary efficacy endpoint estimate for a placebo-controlled efficacy trial must be at least 50 percent, and the statistical success criterion must be that the limit lower than the appropriate alpha the adjusted confidence interval around the primary efficacy end point estimate is (greater than) 30 percent, ”stated CDSCO.
“What this essentially means is that the size of the trial has to be large enough so that if the researchers get exactly 50 percent efficacy, we have to be confident that it will not be less than 30 percent,” said the scientist. Vaccine and Christian Medical College, Vellore. Professor Dr. Gagandeep Kang.
Meanwhile, marking its first major staff layoffs since the Covid outbreak, the BCCI has decided not to renew the annual contracts of 11 coaches at its main National Cricket Academy (NCA), including five retired players from India: Ramesh Powar, SS Das, Hrishikesh Kanitkar, Subroto Banerjee and Sujith Somsundar.
The Indian Express learned that former India captain Rahul Dravid, who had chosen the team after taking over as Head of Cricket at the NCA, informed the coaches last week of his termination of services. Those who have been asked to leave include the stalwart Sitanshu Kotak.
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