UK Vaccine Task Force Chair Kate Bingham said Tuesday that the first generation of COVID-19 vaccines “are likely to be imperfect” and that “they may not work for everyone.”
“However, we do not know if we will ever have a vaccine. It is important to guard against complacency and over-optimism,” Bingham wrote in an article published in The Lancet medical journal.
“The first generation of vaccines are likely to be imperfect, and we must be prepared so that they do not prevent infection, but reduce symptoms, and even then they may not work for everyone or for a long time,” he added.
Bingham wrote that the Vaccine Working Group recognizes that “many, and possibly all, of these vaccines could fail,” adding that attention has focused on vaccines that are expected to elicit immune responses in the population over 65 years of age.
He said that global vaccine manufacturing capacity is grossly inadequate for the billions of doses needed and that UK manufacturing capacity to date has been “just as tight”.
Earlier on Tuesday, a study by scientists at Imperial College London found that antibodies to the new coronavirus declined rapidly in the British population during the summer, suggesting that protection after infection may not be long-lasting and increases the possibility of waning immunity in the community.
The Telegraph newspaper reported that the British government is working on the assumption that the second wave of coronavirus will be more deadly than the first.
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