A day after the Union’s health minister, Harsh Vardhan, said in Parliament that a Covid-19 vaccine is likely to be available early next year, the health ministry detailed on Friday the trials that are being carried out. out today. About 30 Covid-19 vaccines are being developed. Three of them are in a very advanced stage, the ministry said.
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Here are the details
Bharat Biotech: Bharat Biotech International Ltd has developed an inactivated whole virion candidate vaccine for SARS-CoV-2, using the virus isolate (NIV-2020-770) provided by ICMR-National Institute of Virology. Safety and tolerability studies have been conducted in small animals such as rats, mice, and rabbits.
Results: Phase 1 clinical trials have been completed along with parallel studies in hamsters and rhesus macaques.
The trial has revealed excellent safety of the candidate vaccine. Immunogenicity testing is ongoing, according to the statement.
Phase 2 clinical trials are underway
Cadilla Healthcare:
A DNA vaccine has been developed. Preclinical toxicity studies were conducted in mice, rats, rabbits, and guinea pigs. “The vaccine has been found to be safe and immunogenic,” the statement said.
Results: Phase 1 clinical trials have been completed. The trial has revealed excellent safety of the candidate vaccine. Immunogenicity tests are in progress, the ministry said.
Phase 2 clinical trials are ongoing
Serum Institute of India
IBS and ICMR have partnered for the clinical development of two global vaccines.
The Oxford vaccine is in phase 3 clinical trials in Brazil. The ICMR has initiated phase 2 and 3 bridging studies at 14 clinical trial sites, the ministry said.
ICMR and IBS have teamed up for the clinical development of a “glycoprotein subunit nanoparticle adjuvanted vaccine” developed by Novavax of the USA. “The trial will begin in the second half of October after IBS manufactures the vaccine, ”the ministry said.
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