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The first large-scale viral genomic scientific analysis of the 2020 epidemic waves in Hungary has been completed. Hungarian researchers determined the genetic code of hundreds of samples of the Hungarian SARS-CoV-2 virus, which were examined by staff at the Szeged Biological Research Center using evolutionary computer analysis. The main Hungarian university and non-university institutions also participated in the cooperation.
According to the Eötvös Loránd Research Network, the latest project results confirm that the second wave of a new type of coronavirus infection in Hungary, considered SARS-CoV-2, is independent of the spring outbreak in Hungary:
the current epidemiological situation is not the continuation of chains of infection established in the spring and lurking, but the result of reintroductions in mid-summer. Comparative analysis of virus variants revealed by genome sequencing (accurate mapping of viral hereditary material) also clearly shows that while the first wave of spring infection remained local in Hungary due to effective restrictions, in the autumn the national chain and confirms that epidemiological restrictions are essential to prevent or slow the spread of infection.
Prof. Dr. Jakab Ferenc and dr. According to Gábor Kemenesi, two heads of the National Virology Laboratory, it is important that the genetic stock of the SARS-CoV-2 coronavirus is constantly changing, but this change is a relatively slow process compared to the genetic modifications of other viruses (such as the influenza virus). However, natural changes (mutations) in viral inheritance can play an important role in the viability and infectivity of the pathogen, and the temporal and spatial pattern of the mutations provides important information on the spread of the epidemic.
It is also written that the analysis of the evolutionary tree based on the genetic examination of the virus variants shows that the first Hungarian imports detected may have taken place at the end of February and the first half of March, at the time when the first infections affected to western Europe. This means that
It is wrong to believe that the virus has spread before in the country. According to the research, the virus variants that spread in Hungary are basically the same as the virus variants that spread in Europe, the current wave of epidemics is dominated by variants that developed in other European countries during the spring.
The full analysis, which includes the assessment of the virus variants currently spreading in Hungary, can be read here.
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