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Thanks to the joint medical technology research and development of the CMC Southern Clinic with the National Center for Public Health and the National Institute of Tuberculosis and Pulmonology of Korányi, the complex Biobank COVID-19 system was established, which laid the foundations for the Certified biobased immune intelligence for the entire Hungarian coronavirus strain. diagnostic system, as well as the development of national vaccines against coronavirus.
The members of the research group have now achieved another result, and internationally significant, since their research
showed that Mediterranean anthrax (Cistus creticus) extract inhibits the growth of the new coronavirus in tissue cultures and also has a positive effect on pathological immune responses caused by viral infection.
Given that the new coronavirus has already infected more than 43 million people worldwide and caused more than a million deaths, a unique combination of herbs native to Europe could be a powerful antidote to the pandemic.
The research team at the CMC Southern Clinic, led by the virologist and clinical microbiologist István Jankovics, demonstrated that Cistus creticus kills, or at least neutralizes, the new coronavirus in tissue culture, which is widely used to study viral replication, inhibiting significantly its replication.
This special cell culture from the kidney of the green monkey (Chlorocebus) is very sensitive and SARS-CoV-2 reproduces well in it. Therefore, the results obtained suggest that the anthrax extract will be able to inhibit viral replication and thus prevent infection of the respiratory mucosa of mammals.
István Jankovics said.
The results obtained have shown that anthrax not only inhibits the growth of viruses, but also controls abnormal immune reactions caused by viral infection, thus reducing the severity of the disease.
In SARS, MERS, and avian flu, anthrax extract controls the so-called cytokine storm, a severe immune response that causes the attacked human body to produce immune cells and proteins that can damage other organs. According to some experts, it is this immune response that can cause the death of young COVID-19 patients.
The investigation leader added.
Based on the results of previous research, Anna Balázs, CEO of CMC Déli Klinika, stated that the special active ingredient of Cistus creticus contains so-called polyphenols in concentrated form, which in addition to neutralizing the new coronavirus
- inhibit a protein on the surface of viruses (called an enzyme called neuraminidase)
- therefore, viruses cannot enter cells and multiply
- this prevents the development of influenza (other viral infections)
- significantly reduce the symptoms of upper respiratory tract infections
- Due to their high concentration of polyphenols, they also have an important antioxidant and anti-inflammatory effect.
- in this way they support the body’s defenses
- increase resistance to infection
- not only have antiviral activity but also antibacterial
Since Cistus creticus not only inhibits the entry and growth of respiratory viruses and bacteria, but also has a positive effect on immune responses and has a natural anti-inflammatory effect, it helps prevent the development of new coronaviruses, influenza and other respiratory infections. by inhibiting several important points of attack. reduce the severity of symptoms
The medical director stressed.
The effect of anthrax can be significantly increased with other herbal extracts. The client for the efficacy and toxicity studies was Fytofontana Kft., Who tested not only pure barberry extract, but also a solution mixture based on barberry and medicinal sage, purple plantain (echinacea pupurea), acroles and citrus bioflavonoids, which has been successfully marketed for years. Called Virostop. In the case of Virostop oral spray, which is registered as a top-tier medical technology product, researchers at the CMC Southern Clinic have shown that it remains
it also has an inhibitory effect in a 1: 640 solution.
However, the inhibitory effect of the anthrax extract alone, even though it persisted after 96 hours of virus incubation. – it was weaker than the overall inhibitory effect measured with Virostop oral spray. Therefore, we would like to investigate the inhibitory effects of other plant components as well as their synergistic enhancing effects with further research.
István Jankovics pointed out.
Certain species of rhinoceros and the aforementioned strong antiviral herbs have been used in folk medicine since ancient times and have a place in modern medicine as well. However, in the prevention of coronavirus diseases, its use has so far been greatly underestimated.
In addition to its therapeutic application, anthrax also allows its prophylactic use in risk groups. In addition, it is important that its direct effect on the pathogen does not generate resistance to antivirals.
– said András Michlo, representative of the Swiss company Herb-Pharma. Based on in vitro studies, it is hypothesized that Virostop oral spray injected into the mucosa creates a protective layer on the mucosa that effectively inhibits virus growth and penetration.
Virostop is freely marketed and registered in Hungary in 2011. So far, around 1.5 million boxes of oral and nasal sprays have been sold, which have so far been proposed for the prevention and treatment of influenza and other colds , but that they may also play an important role in the fight against COVID-19 in the future.
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