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Hungarian experts examined what was happening in the country at the end of the first month of the epidemic, when restrictive measures were introduced: where did the viruses come from in Hungary and how actively did they spread in Hungary. After sequencing the viral genomes, we had to resort to complex genetic analyzes – an excellent professional network was formed in the country, so thanks to scientists from more than five Hungarian research workshops, we can now get an answer, it appeared on page from Virology Pécs Facebook.
Multiple introductions
The figures presented are based on a web-based evolutionary phylogenetic approach, which provides excellent support for the rest. From both analyzes it is clear that
There have been multiple and parallel introductions, mainly of European origin.
This means that, as a result of the pan-European closure wave, people returned to their homes in a relatively short period of time, with which the virus came from various sources. This does not mean that it has not happened before, but it has taken place throughout this scenario in the time period examined by the experts. However, viruses from other continents can also be detected, their origins go back to China or the United States. It is important to note that this is the most likely image that can be delineated based on the currently known genomic dataset.
PTE Virology Research Group
Lucky time
At home, at the beginning of the restrictive measures, we can see local propagation chains and, in mid-March, you can see local infections in various parts of the country, which can be deduced from the degree of genetic similarity. Based on this, we can say that it was a fortunate moment to introduce restrictive measures in the entire Central European region at that time:
there was a good chance that the many introductory events would not become a series of major dispersal chains or even epidemic foci.
Based on current international data, a similar situation can be observed in Poland. The movement of people in Central and Eastern Europe, which started at the beginning of the European closings, may have been the main driving force. And Western Europe and the terrible scenario there have given other countries and our entire region time to introduce early action. And we could spend that time building diagnostic and health capacity, which will have to be leveraged in the current ongoing struggle.
PTE Virology Research Group
The virus continues to circulate here.
At this stage of the epidemic, the most severe discipline of the population and the rapid response of health authorities to the rapid and effective isolation of patients are extremely important. Do not let anyone fool you, the virus continues to circulate among us, it is very important to be aware of this.
All of these results contributed greatly to the spread of SARS-2, a pan-European scenario related to human movement. We were also able to place the first virus sequences in Hungary on a “map” of the global network, in the framework of extensive internal cooperation, in cooperation with our excellent scientists.
The description of the scenario and phenomenon described in the course of greater control of the epidemic provides important information for decision-makers and the unions involved in control. In addition, it will be an important aspect in other epidemics in the future, the staff of the PTE Virology Research Group will close the entrance.
Featured image illustration. Photo: János Marjai / 24.hu
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