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10:00 a.m.
Saturday 02 May 2020
I wrote- Amira Helmy
Dr. Alaa Hashish, Infectious Diseases Officer at the WHO Egypt office, revealed, in an interview with “Masrawy”, that there are soon to be several REMDIVESIVER packages available in Egypt, to start using it in clinical trials of ( Covid 19) caused by a virus. Novelty Crown.
The United States Food and Drug Administration plans to announce the issuance of its emergency approval for the use of the drug “Remdisever” for the purpose of treatment, after the results of its experience showed its success in shortening the time of Recovery.
Remdesivir presented a glimmer of hope in the fight against the Corona virus this week, when the results of a promising clinical trial were published, after the experiment revealed that it could speed recovery in some patients. The American immunologist, Dr. Anthony Fossey, described it as a “very important first step” in treating the virus, and said the United States Food and Drug Administration would probably agree to use the drug against the virus. ” very quickly “.
Gilead Sciences is committed to “providing adequate supplies to patients around the world.”
What is Ramesdiver and why was it developed?
It is an experimental antiviral medication that was first developed by the American pharmaceutical company Gilead Sciences to treat Ebola.
The drug, developed in 2015, showed early promise in an animal study and was later launched in the Democratic Republic of the Congo, but ultimately failed as an effective treatment for Ebola, according to Russia Today.
Speaking to the New York Post, Peter Bates, a former assistant commissioner for the Food and Drug Administration, said: “He was never promising; relatively unsuccessful against Ebola. So doctors said to see if he works against Coffid-19.”
How effective is it against Corona Virus?
The results of a clinical trial, conducted on more than 1,000 people, showed that patients with Covid-19 respiratory problems improved 31% faster than those taking the placebo, according to the National Institute of Allergy and Infectious Diseases.
But Bates cautioned that the drug showed benefit only in patients, who were hospitalized by the elderly and who had previous or respiratory health problems. “It saves lives, but it doesn’t change the rules of the game. Clinical trials have shown that it has led to recovery in 4-10% of patients with severe disease,” he said.
How does remisevir work?
To do the job, the drug mimics adenosine, one of the four building blocks of viral RNA, also known as RNA, and when a virus fuses a remedivifer into its genome instead of adenosine, it becomes unable to reproduce, according to AFP.
“It enters the viral RNA and causes the virus to end prematurely,” said Bates.
– What are the side effects of Remsdevir?
According to the results of the most recent study published by Gilead Sciences, the most common adverse reactions were nausea and acute respiratory failure. About 7% of patients experienced an increase in liver enzymes.
– How much will Remisdiver cost?
This is not yet clear, though Daniel Oday, CEO of Gilead Sciences, told Stat News this week that the company is donating 1.5 million doses of the drug, about 140,000 courses of treatment, to hospitals, and has promised to “work with the government and with healthcare systems to guarantee access to medicine and make it accessible to governments in the future. “
How should we be excited about the remedy?
It is just a drug, not a miracle cure, and doctors say they need to know more about it. Some experts consider it “a good guide” that could pave the way for better treatments.
“Clinical trials have shown a very positive effect in those who were hospitalized. But at the moment, it is still an experimental drug,” said Bates.
