Discovered a vulnerability that allowed the Corona virus to hide from the immune system



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Scientists have revealed the structure and shape of the corona virus that causes the global pandemic with new details, in an attempt to learn more about it and help develop a vaccine.

And according to what was published by the “Daily Mail” website, a three-dimensional model created at the University of Southampton in Great Britain reveals the camouflage of the virus that it uses to hide from the human immune system.

News of the discovery of a vulnerability in Corona
News of the discovery of a vulnerability in Corona

The first model of protein mutations appears on the surface of the virus, which are the primary targets of antibody and vaccine research, and researchers say that sugars on the surface allow them to infiltrate the body, without discovering a wonderful disguise.

The researchers also found that the new coronavirus is not protected or disguised as some viruses, such as HIV, where the research team, led by Professor Max Crispin, claims that the model will provide “crucial and encouraging” information to the scientists who make it. a vaccine.

Professor Crispin explains that the Corona virus has a large number of nails that come out of its surface, which it uses to bind cells and penetrate them into the human body.

These nails are covered in sugars, known as glycans, that mask their viral proteins and help them evade the body’s immune system.

The research was published online on bioRxiv before printing and is not yet a journal in which the theory has not been reviewed, which is the process in which other scholars examine the research.

Professor Crispin said: “By being covered with sugars, these viruses can hide from the immune system, but one of the main findings of our study is that despite the amount of sugars present, this coronavirus is not protected like other viruses.”

Viruses like HIV, which remain in a host, must constantly evade the immune system and have a really dense layer of galacan as the shield of the immune system, but in the case of the coronavirus, the lower armor of the sugars attached to it may reflect a “hit and run” virus. Transmitted from one person to another.

However, the low glucan density means that there are fewer barriers for the immune system to neutralize the virus with antibodies. So this is a very encouraging message for vaccine development, and the research was done using equipment previously provided with a grant from the Bill and Melinda Gates Foundation through collaboration to discover the AIDS vaccine.

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