New research suggests that children who have previously caught a common cold have coronavirus antibodies that prevent them from developing a hyper-inflammatory condition called MIS-C.
This rare disease is caused by the SARS-Covi-2 coronavirus infection, the same pathogen responsible for the current Covid-19 epidemic.
Research has shown that this condition, known as multisystem inflammatory syndrome in children (MIS-C), is different from both Kovid-19 and Kawasaki disease.
However, little is known about why some children develop MIS-C symptoms a month after being infected with the coronavirus.
Indicators of the disease include rash, fever and abdominal pain as well as conjunctivitis, cough and headache.
Experts from Sweden’s Karolinska Institute have compared healthy children with young people with MIS-C and Kawasaki disease.
Blood tests of 13 MIS-C patients, 28 Kawasaki patients and uninfected children reported a lack of antibodies against the common cold in the MIS-C group.
Researchers say that antibodies obtained after a common cold infection may play a role in controlling the development of MIS-C.
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Experts from Sweden’s Karolinska Institute have compared healthy children with young people with MIS-C and Kawasaki disease. Illustrated, symptoms of both diseases
Bertie Brown was admitted to Worcestershire Royal Hospital on her second birthday this year, after developing a fever and rash on her body, which is believed to be MIS-C.
Researchers have found evidence of antibodies to coronavirus HQA1 and betacoronavirus1, both of which we know as the common cold.
In contrast to children with Kawasaki disease and children with mild COVID-19, children with MIS-C lacked antibodies to this mild coronavirus.
The lead author of the study, Dr. Peter Brodyne told the Mail Line that there is currently no way to test the theory that the common cold immunity is protected against MIS-C by antibodies, but it seems that this may be the case.
‘Immunity to the common cold coronavirus is usually quite shortened, and MIS-C usually affects adolescents, and the lack of these common cold coronavirus-antibodies in MIS-C patients was the only group, suggesting that it is possible. He said that having such antibodies could provide protection against MIS-C. ‘
They believe that the common cold CoV antibodies and memory B-cells that produce them can recognize and bind the SARS-CoV-2 virus.
‘Such events will make a start to protect the immune system against the virus and enable a more effective antibody response that directly zooms in on the right parts of the new virus and helps to deactivate it.’
MIS-C is a type of toxic shock syndrome that causes the body’s immune system to attack its own organs. It is believed to be due to infection with the coronavirus SARS-Covy-2
Another finding of the study is that many antibodies are present in MIS-C patients that attack the body’s own proteins, a process known as cytokine in the storm.
This form of immune self-destruction is thought to be a major contributor to severe cases of MIS-C.
However, while both diseases are aggravated by cytokine hurricanes, the processes for MIS-C and Covid-19 are different.
Scientists are unable to explain why adults develop COVID-19 when children are infected with MIS-C, even though they have the same virus.
The hyper-inflammatory condition is thought to be a delayed immune response to infection, which converts the traditional throat and nose.
Consequently, the only reliable way to confirm and diagnose symptoms is antibody testing.
As the world became associated with the COVID-19 epidemic, Kawasaki-like conditions were emerging and the frequency was increasing.
Very little is known about MIS-C, except that it is rarely caused by SARS-COV-2 and has symptoms similar to, but not identical to, Kawasaki disease.
It affects children or young adults almost exclusively, unlike COVID-19 which rarely harms young people.
It emerged earlier this year as parents shared heart-wrenching images of their children at a hospital hospital covered in bright red spots.
In May, during the peak of the Covid-19 outbreak, doctors in the U.S. said inflammatory conditions could affect adults in their early 20s.
Although casualties from MIS-C are very rare, it has been noted. A 14-year-old boy died of the disease in London. And at least four U.S. Death report in.
Mailline Nalai reported in May that Birmingham-based researchers had found the first glimpse of evidence of a Kawasaki-like condition, later renamed MIS-C, caused by SARS-CV-2.
This was confirmed in August when academics at King’s College London published a peer-reviewed study confirming the relationship.
Dr. Manu Shankar-Hari, co-author of the August research, told Mailline Naline: ‘There is no diagnostic test for Kawasaki disease or MIS-C.
‘There are shared clinical facilities. Thus, if your child is upset, it is best to seek medical advice.
‘This research highlights that, unlike Kawasaki disease, MIS-C is associated with SARS-CV-2 infection with a variety of clinical and immune findings.’
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