Brain-destroying piano disease is becoming more common, the study finds


An image of a sample of human brain tissue under a microscope.  It shows so-called spongy pores caused by Kreitzfeldt-Jacob disease.

An image of a sample of human brain tissue under a microscope. That Display The so-called spongy pores caused by Kreitzfeldt-Jacob disease.
Image: Sheriff Zaki, Woon-Ju Shi / CDC

New research from Japan suggests that due to the aging population, a rare brain-destroying disease caused by rogue prion protein may be common.

Learning, Published In the journal Scientific Reports last month, the Japanese government collected data from 2005 to 2005. 2014 on residents over 50 years of age Diagnosed with Kretzfeldt-Jacob disease (CJD). In those years, the study found that the average incidence rate of CJD increased by 6.4 percent annually. This increase was most pronounced in people over the age of 70, but researchers also held this pattern when calculating age.

“In our study, the death-death rate in Japan between 2005 and 2014, and the incidence rate associated with CJD – increased dramatically even after age-adjustment,” he wrote.

Prenatal diseases such as CJD are thought to be naturally occurring and harmful prein proteins in the brain. This successful protein has an unusual ability to turn other normal loved ones into folds like them, initiating a very slow-moving cascade of destruction that spreads throughout the brain and leaves behind typical spongy microscopic pores, which Can be seen in the victim The brain after death. Dementia-like symptoms Loss of muscle control will not appear for years Decades, prion depending on the disease, but once they die Quickly down. To date, there is no cure for Prion diseases, and their mortality rate after the onset of symptoms is 100%.

Some prine diseases are transmissible to humans or from animals to humans. The person then feels infected Exposure to brain or organ tissue, which is contaminated by a loved one (contaminated) Cannibal). Others are inherited, due to a genetic mutation that is more likely to appear at a certain stage of your life in a bad life. Most often, however, prunes appear for obvious reasons, called sporadic prion disease.. CJD comes in all three forms, although the sporadic CJD is the most common version, accounting for 85% of cases. Whatever the form, CJD is the most common Prion disease.

Although there is no single cause for most cases of CJD, age is considered an important risk factor. And this current study is not the first to highlight a clear increase in CJD with time associated with age. Similar trends have been found in many countries, including other research America. But so is Japan Known For the world’s largest elderly population, more than 65% to more than 20%. It is therefore likely that there will be no age related link with CJD There’s more to be clear – a fate that researchers are understandably concerned about.

That said, CJD and all the piano diseases are outstanding Rare. In 2017, for example, only 511 Americans were diagnosed with CJD, according to the Centers for Disease Control and Prevention. But these mysterious diseases may be the most ruthless reminder of the stress that comes with the aging population, in Japan and elsewhere. There are other causes of dementia, such as Alzheimer’s Expected Incidents are also set to increase in the years to come, and especially in the U.S. Can affect places like, where other long-term conditions for older Americans have also increased. Over time

The authors warn that CJD and other forms of dementia will affect not only those who develop it, but also families and other caregivers who will struggle to care for them, the authors warn. This is a serious economic burden, he wrote, “emphasizing the need for a preventive action with a particular focus on policymakers’ focus and readiness to control the spread of dementia.”

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